YRC Public Data Repository - Protein Structure Prediction

Protein:	COX11_MOUSE
Organism:	Mus musculus
Length:	275 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COX11_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|109488791, gi... - ref\|XP_213433.2\| similar to COX11 homolog; cytochrome c oxidase subunit 11; cytochrome c oxidase ass...	490.0	[0..1]	[275..1]
gi\|60826960 - gi\|60826960\|gb\|AAX36778.1\| COX11-like cytochrome c oxidase assembly protein [synthetic construct]	472.0	[0..1]	[275..1]
COX11 - COX11 cytochrome c oxidase assembly homolog (yeast) gi\|60814946 - gi\|60814946\|gb\|AAX36326.1\| COX11-like cytochrome c oxidase assembly protein [synthetic construct]	471.0	[0..1]	[275..1]
gi\|55730891 - gi\|55730891\|emb\|CAH92164.1\| hypothetical protein [Pongo abelii] gi\|55730891\|emb\|... - hypothetical protein [Pongo pygmaeus]	456.0	[0..1]	[275..1]
gi\|109114390 - gi\|109114390\|ref\|XP_001102862.1\| PREDICTED: similar to COX11 homolog [Macaca mulatta]	455.0	[0..1]	[275..1]
gi\|73966488 - gi\|73966488\|ref\|XP_866470.1\| PREDICTED: similar to COX11 homolog isoform 2 [Canis familiaris]	426.0	[0..1]	[275..1]

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Predicted Domain #1

Region A:
Residues: [1-87]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGLWCPGWR LVASCGRGWR QPGWSGRTVV NAELVLRPGW DGLGGAERGL RRLGTWKRPC  60
   61 GVRGPATQPP RRPRSSNPFQ RAQEDEW

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.234	a.64.1	Saposin
View	Download	0.358	a.81.1	N-terminal domain of DnaB helicase
View	Download	0.224	a.64.1	Saposin

Predicted Domain #2

Region A:
Residues: [88-275]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRRNKTVLTY VAAAAVGMLG ASYAAVPLYR LYCQTTGLGG SAVAGHSSDQ IENMVPVKDR  60
   61 VIKVTFNADV HASLQWNFRP QQTEIYVVPG ETALAFYKAK NPTDKPVIGI STYNVVPFEA 120
  121 GQYFNKIQCF CFEEQRLNPQ EEVDMPVFFY IDPEFAEDPR MVNVDLITLS YTFFEAKEGH 180
  181 KLPVPGYN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	64.39794
Match:	1so9A
Description:	Solution Structure of apoCox11, 30 structures
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.26238051646126	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: