YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|46575936, gi\|...
Organism:	Mus musculus
Length:	252 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|46575936, gi|....

Description	E-value	Query Range	Subject Range
gi\|55661706, gi\|... - gi\|72533644\|gb\|AAI00923.1\| Fibroblast growth factor 14 [Homo sapiens], gi\|71682675\|gb\|AAI00922.1\| Fi... gi\|109121206 - gi\|109121206\|ref\|XP_001093457.1\| PREDICTED: fibroblast growth factor 14 isoform 1 [Macaca mulatta] gi\|114650545 - gi\|114650545\|ref\|XP_001150217.1\| PREDICTED: fibroblast growth factor 14 isoform 2 [Pan troglodytes] CCDS9500.1_1 - null	334.0	[0..1]	[252..1]
gi\|45382137, gi\|... - gi\|6911123\|gb\|AAF31393.1\|AF199606_1 fibroblast growth factor homologous factor 4 isoform 1B [Gallus ...	322.0	[0..1]	[252..1]
gi\|19070525 - gi\|19070525\|gb\|AAL83904.1\|AF348523_1 fibroblast growth factor-like factor-4D [Rattus norvegicus]	255.0	[0..54]	[252..13]
gi\|28191242 - gi\|28191242\|gb\|AAO33291.1\| fibroblast growth factor-like protein [Meleagris gallopavo]	250.0	[0..47]	[252..29]
gi\|73989458 - gi\|73989458\|ref\|XP_542656.2\| PREDICTED: similar to fibroblast growth factor 14 [Canis familiaris]	249.0	[0..62]	[252..57]
FGF14_MOUSE - Fibroblast growth factor 14 OS=Mus musculus GN=Fgf14 PE=2 SV=1	248.0	[0..62]	[252..57]
gi\|109132469 - gi\|109132469\|ref\|XP_001084216.1\| PREDICTED: fibroblast growth factor 13 isoform 2 [Macaca mulatta] gi\|221045728, gi... - gi\|221045728\|dbj\|BAH14541.1\| unnamed protein product [Homo sapiens], gi\|221041872\|dbj\|BAH12613.1\| un...	248.0	[0..47]	[252..48]
gi\|148230685, gi... - gi\|49899696\|gb\|AAH76721.1\| Fgf13-prov protein [Xenopus laevis], gi\|148230685\|ref\|NP_001086499.1\| fib...	247.0	[0..47]	[252..48]

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Predicted Domain #1

Region A:
Residues: [1-252]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKPVPLFRR TDFKLLLCNH KGLFFLRVSK LLGCFSPKSM WFLWNIFSKG THMLQCLCGK  60
   61 SLKKNKNPTD PQLKGIVTRL YCRQGYYLQM HPDGALDGTK DDSTNSTLFN LIPVGLRVVA 120
  121 IQGVKTGLYI AMNGEGYLYP SELFTPECKF KESVFENYYV IYSSMLYRQQ ESGRAWFLGL 180
  181 NKEGQVMKGN RVKKTKPAAH FLPKPLEVAM YREPSLHDVG ETVPKAGVTP SKSTSASAIM 240
  241 NGGKPVNKCK TT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.522879
Match:	1q1uA
Description:	Crystal structure of human FHF1b (FGF12b)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.90110516688922	bayes_pls_golite062009
receptor binding	2.16557070623757	bayes_pls_golite062009
protein binding	1.94397222237906	bayes_pls_golite062009
growth factor activity	1.45668559810417	bayes_pls_golite062009
cytokine activity	0.491912278395019	bayes_pls_golite062009
fibroblast growth factor receptor binding	0.379391310291065	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: