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View Structure Prediction Details

Protein: INS2_MOUSE
Organism: Mus musculus
Length: 110 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for INS2_MOUSE.

Description E-value Query
Range		 Subject
Range
INS1_RAT - Insulin-1 OS=Rattus norvegicus GN=Ins1 PE=1 SV=1
 144.0 [0..1] [110..1]
INS_MACFA - Insulin OS=Macaca fascicularis GN=INS PE=3 SV=1
 142.0 [0..1] [110..1]
INS_CHLAE - Insulin OS=Chlorocebus aethiops GN=INS PE=1 SV=1
 142.0 [0..1] [110..1]
INS - insulin
gi|22901140 - gi|22901140|gb|AAN06935.1| insulin precursor [Gorilla gorilla]
gi|123992113, gi... - gi|61361299|gb|AAX42026.1| insulin [synthetic construct], gi|61361296|gb|AAX42025.1| insulin [synthe...
INS_GORGO - Insulin OS=Gorilla gorilla gorilla GN=INS PE=3 SV=1
 141.0 [0..1] [110..1]
INS_PONPY - Insulin OS=Pongo pygmaeus GN=INS PE=3 SV=1
 141.0 [0..1] [110..1]
gi|30584395, gi|... - gi|60653575|gb|AAX29481.1| insulin [synthetic construct], gi|60653573|gb|AAX29480.1| insulin [synthe...
 141.0 [0..1] [110..1]
INS_CRILO - Insulin OS=Cricetulus longicaudatus GN=INS PE=1 SV=2
gi|305360, gi|21... - gi|305360|gb|AAA37089.1| preproinsulin, gi|2137094|pir||I48166 insulin precursor - golden hamster
 141.0 [0..1] [110..1]
INS_PSAOB - Insulin OS=Psammomys obesus GN=INS PE=3 SV=1
 141.0 [0..1] [110..1]
INS_PANTR - Insulin OS=Pan troglodytes GN=INS PE=1 SV=1
 141.0 [0..1] [110..1]

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Predicted Domain #1
Region A:
Residues: [1-110] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALWMRFLPL LALLFLWESH PTQAFVKQHL CGSHLVEALY LVCGERGFFY TPMSRREVED  60
   61 PQVAQLELGG GPGAGDLQTL ALEVAQQKRG IVDQCCTSIC SLYQLENYCN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.39794
Match: 1efeA
Description: Insulin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.18233774896601 bayes_pls_golite062009
receptor binding 1.14174731640237 bayes_pls_golite062009
protein binding 0.921884418602488 bayes_pls_golite062009
insulin receptor binding 0.80057749532609 bayes_pls_golite062009
insulin-like growth factor receptor binding 0.58174700707775 bayes_pls_golite062009
protein complex binding 0.15962592539541 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle