YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|31980617, gi\|...
Organism:	Mus musculus
Length:	232 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|31980617, gi|....

Description	E-value	Query Range	Subject Range
gi\|73999473 - gi\|73999473\|ref\|XP_544116.2\| PREDICTED: similar to vesicle transport through interaction with t-SNAR...	199.0	[0..8]	[232..176]
VTI1B_MOUSE - Vesicle transport through interaction with t-SNAREs homolog 1B OS=Mus musculus GN=Vti1b PE=1 SV=1	173.0	[0..1]	[232..1]
VTI1B_BOVIN - Vesicle transport through interaction with t-SNAREs homolog 1B OS=Bos taurus GN=VTI1B PE=2 SV=1	166.0	[0..1]	[232..1]
gi\|55623560 - gi\|55623560\|ref\|XP_517549.1\| PREDICTED: similar to vesicle soluble NSF attachment protein receptor V...	160.0	[0..1]	[232..1]
gi\|47523922, gi\|... - gi\|47523922\|ref\|NP_999602.1\| NFS protein [Sus scrofa], gi\|40846452\|gb\|AAR92482.1\| NFS [Sus scrofa], ...	158.0	[0..1]	[230..1]
gi\|61358053 - gi\|61358053\|gb\|AAX41494.1\| vesicle transport through interaction with t-SNAREs-like 1B [synthetic co... gi\|54696782 - gi\|54696782\|gb\|AAV38763.1\| vesicle transport through interaction with t-SNAREs homolog 1B (yeast) [H...	156.0	[0..1]	[232..1]
gi\|61368200, gi\|... - gi\|61368200\|gb\|AAX43127.1\| vesicle transport through interaction with t-SNAREs-like 1B [synthetic co...	156.0	[0..1]	[232..1]

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Predicted Domain #1

Region A:
Residues: [1-116]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAASAASSEH FEKLHEIFRG LLEDLQGVPE RLLGTAGTEE KKKLVRDFDE KQQEANETLA  60
   61 EMEEELRYAP LTFRNPMMSK LRNYRKDLAK LHREVRSTPL TAAPGGRGDL KYGTYT

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.56
Match:	1vcsA
Description:	Solution Structure of RSGI RUH-009, an N-Terminal Domain of Vti1a [Mus musculus]
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphatidic acid binding	4.43639331290696	bayes_pls_golite062009
SNAP receptor activity	2.87584659156593	bayes_pls_golite062009
calcium channel inhibitor activity	2.6070306401994	bayes_pls_golite062009
binding	2.10865031355861	bayes_pls_golite062009
arachidonic acid binding	2.07456472080416	bayes_pls_golite062009
protein binding	1.71065434412329	bayes_pls_golite062009
transporter activity	1.70608335538771	bayes_pls_golite062009
substrate-specific transporter activity	1.43050612049396	bayes_pls_golite062009
myosin head/neck binding	1.33894171285049	bayes_pls_golite062009
transmembrane transporter activity	1.13402377922348	bayes_pls_golite062009
protein transporter activity	0.874305466215024	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.641704633739097	bayes_pls_golite062009
SNARE binding	0.387098576112631	bayes_pls_golite062009
ion transmembrane transporter activity	0.36574534937133	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [117-232]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LENEHLNRLQ SQRALLLQGT ESLNRATQSI ERSHRIATET DQIGTEIIEE LGEQRDQLER  60
   61 TKSRLVNTNE NLSKSRKILR SMSRKVITNK LLLSVIILLE LAILVGLVYY KFFRHH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.0
Match:	1gl2C
Description:	Vesicle ransport v-SNARE protein VTI1b
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: