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View Structure Prediction Details

Protein: gi|114651889
Organism: Pan troglodytes
Length: 580 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|114651889.

Description E-value Query
Range
Subject
Range
gi|30353931 - gi|30353931|gb|AAH52244.1| Methyltransferase like 3 [Homo sapiens]
0.0 [1..580] [1..580]
gi|114651891 - gi|114651891|ref|XP_001154543.1| PREDICTED: methyltransferase like 3 isoform 2 [Pan troglodytes]
0.0 [1..580] [1..592]
gi|109082747 - gi|109082747|ref|XP_001097947.1| PREDICTED: similar to methyltransferase like 3 isoform 2 [Macaca mu...
0.0 [1..580] [1..580]
gi|77627973, gi|... - gi|77627973|ref|NP_062695.2| methyltransferase-like 3 [Mus musculus], gi|26351497|dbj|BAC39385.1| un...
0.0 [1..580] [1..580]
gi|73977380 - gi|73977380|ref|XP_532627.2| PREDICTED: similar to methyltransferase like 3 isoform 1 [Canis familia...
0.0 [1..580] [1..580]
gi|67078430, gi|... - gi|67078430|ref|NP_001019965.1| methyltransferase-like 3 [Rattus norvegicus], gi|66910595|gb|AAH9740...
0.0 [1..580] [1..580]

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Predicted Domain #1
Region A:
Residues: [1-141]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDTWSSIQA HKKQLDSLRE RLQRRRKQDS GHLDLRNPEA ALSPTFRSDS PVPTAPTSGG  60
   61 PKPSTASAVP ELATDPELEK KLLHHLSDLA LTLPTDAVSI CLAISTPDAP ATQDGVESLL 120
  121 QKFAAQELIE VKRGLLQDDA H

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [142-231]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTLVTYADHS KLSAMMGAVA EKKGPGEVAG TVTGQKRRAE QDSTTVAAFA SSLVSGLNSS  60
   61 ASEPAKEPAK KSRKHAASDV DLEIESLLNQ 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [232-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSTKEQQSKK VSQEILELLN TTTAKEQSIV EKFRSRGRAQ VQEFCDYGTK EECMKASDAD  60
   61 RPCRKLHFRR IINKHTDESL GDCSFLNTCF HMDTCKYVHY EIDACMDSEA PGSKDHTPSQ 120
  121 ELALTQSVGG DS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [364-580]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SADRLFPPQW ICCDIRYLDV SILGKFAVVM ADPPWDIHME LPYGTLTDDE MRRLNIPVLQ  60
   61 DDGFLFLWVT GRAMELGREC LNLWGYERVD EIIWVKTNQL QRIIRTGRTG HWLNHGKEHC 120
  121 LVGVKGNPQG FNQGLDCDVI VAEVRSTSHK PDEIYGMIER LSPGTRKIEL FGRPHNVQPN 180
  181 WITLGNQLDG IHLLDPDVVA RFKQRYPDGI ISKPKNL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.04
Match: 1g60A
Description: Methyltransferase mboII
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
methyltransferase activity 3.68431317301075 bayes_pls_golite062009
N-methyltransferase activity 3.64494850793256 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 3.60853685152199 bayes_pls_golite062009
protein methyltransferase activity 3.51986359093355 bayes_pls_golite062009
DNA-methyltransferase activity 3.47923436720314 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 2.91374296950366 bayes_pls_golite062009
histone methyltransferase activity 2.666651371662 bayes_pls_golite062009
RNA methyltransferase activity 2.63941856307703 bayes_pls_golite062009
protein-arginine N-methyltransferase activity 1.99340565364513 bayes_pls_golite062009
arginine N-methyltransferase activity 1.99340565364513 bayes_pls_golite062009
transferase activity 1.97261773840408 bayes_pls_golite062009
rRNA methyltransferase activity 1.85380504590369 bayes_pls_golite062009
binding 1.65046086869658 bayes_pls_golite062009
histone-arginine N-methyltransferase activity 1.64765900536818 bayes_pls_golite062009
transcription regulator activity 1.59599828300594 bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity 1.5743030926483 bayes_pls_golite062009
DNA binding 1.48691268044769 bayes_pls_golite062009
tRNA methyltransferase activity 1.38914410921124 bayes_pls_golite062009
nucleic acid binding 1.36595590938226 bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity 1.27753381141602 bayes_pls_golite062009
DNA (cytosine-5-)-methyltransferase activity 1.23915163423518 bayes_pls_golite062009
catalytic activity 1.16970557486814 bayes_pls_golite062009
RNA binding 1.10288658549985 bayes_pls_golite062009
protein-arginine omega-N symmetric methyltransferase activity 0.862671287243863 bayes_pls_golite062009
rRNA (uridine) methyltransferase activity 0.837734735695963 bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific) 0.735680462496249 bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity 0.51222176401398 bayes_pls_golite062009
tRNA (cytosine)-methyltransferase activity 0.325961687103877 bayes_pls_golite062009
tRNA (cytosine-5-)-methyltransferase activity 0.325961687103877 bayes_pls_golite062009
histone binding 0.230289474831554 bayes_pls_golite062009
rRNA (adenine) methyltransferase activity 0.113328595762489 bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity 0.0390774859535424 bayes_pls_golite062009
mRNA methyltransferase activity 0.03091406523028 bayes_pls_golite062009
mRNA (guanine-N7-)-methyltransferase activity 0.03091406523028 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle