YRC Public Data Repository - Protein Structure Prediction

Protein:	HXC4_RAT
Organism:	Rattus norvegicus
Length:	76 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HXC4_RAT.

Description	E-value	Query Range	Subject Range
HXA7_MOUSE - Homeobox protein Hox-A7 OS=Mus musculus GN=Hoxa7 PE=2 SV=2	127.0	[0..2]	[75..120]
gi\|158711670, gi... - gi\|62647267\|ref\|XP_575478.1\| PREDICTED: similar to Hoxa7 [Rattus norvegicus], gi\|158711670\|ref\|NP_00...	127.0	[0..2]	[75..120]
gi\|15425738, gi\|... - gi\|15425738\|dbj\|BAB64346.1\| homeotic protein [Daphnia magna], gi\|109944931\|dbj\|BAE96993.1\| Antennape...	125.0	[0..2]	[73..537]
gi\|109944934 - gi\|109944934\|dbj\|BAE96995.1\| Antennapedia [Moina macrocopa]	125.0	[0..2]	[73..438]
gi\|3420834 - gi\|3420834\|gb\|AAC31944.1\| Sex combs reduced homeotic protein [Anopheles gambiae] gi\|31205335, gi\|... - gi\|31205335\|ref\|XP_311616.1\| AGAP004659-PA [Anopheles gambiae str. PEST], gi\|30177656\|gb\|EAA07257.2\|...	122.0	[0..5]	[74..274]
gi\|798833 - gi\|798833\|emb\|CAA54348.1\| unnamed protein product [Drosophila melanogaster]	122.0	[0..5]	[74..318]
gi\|6513841 - gi\|6513841\|gb\|AAD01939.2\| homeobox protein HOXA7 [Homo sapiens]	121.0	[0..2]	[75..121]

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Predicted Domain #1

Region A:
Residues: [1-76]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LVVMLESRFP GPARGVANCR QQVLELEKEF HYNRYLTRRR RIEIAHSLCL SERQIKIWFQ  60
   61 NRRMKWKKDH DSPTPK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.69897
Match:	1pufA
Description:	Crystal Structure of HoxA9 and Pbx1 homeodomains bound to DNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	1.26571574724964	bayes_pls_golite062009
binding	1.25140430108186	bayes_pls_golite062009
DNA binding	1.04913281181737	bayes_pls_golite062009
nucleic acid binding	0.787927191745053	bayes_pls_golite062009
transcription factor activity	0.77563923452142	bayes_pls_golite062009
protein binding	0.134872960372588	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: