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View Structure Prediction Details

Protein: GDIR1_RAT
Organism: Rattus norvegicus
Length: 204 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GDIR1_RAT.

Description E-value Query
Range
Subject
Range
gi|7245833 - gi|7245833|pdb|1DOA|B Chain B, Structure Of The Rho Family Gtp-Binding Protein Cdc42 In Complex With...
338.0 [0..1] [204..16]
gi|73964747 - gi|73964747|ref|XP_849933.1| PREDICTED: similar to Rho GDP dissociation inhibitor (GDI) alpha [Canis...
338.0 [0..1] [204..1]
gi|36038, gi|189... - gi|36038|emb|CAA45344.1| rho GDP dissociation inhibitor (GDI) [Homo sapiens], gi|189065429|dbj|BAG35...
337.0 [0..1] [204..1]
gi|61366982, gi|... - gi|61366989|gb|AAX42936.1| Rho GDP dissociation inhibitor alpha [synthetic construct], gi|61366982|g...
337.0 [0..1] [204..1]
gi|13435747 - gi|13435747|gb|AAH04732.1| Rho GDP dissociation inhibitor (GDI) alpha [Mus musculus]
332.0 [0..1] [204..1]
gi|53126513, gi|... - gi|53126513|emb|CAG30962.1| hypothetical protein [Gallus gallus], gi|124249432|ref|NP_001074340.1| R...
329.0 [0..1] [204..1]
gi|28502871, gi|... - gi|55742559|ref|NP_998626.1| Rho GDP dissociation inhibitor (GDI) alpha [Danio rerio], gi|28502871|g...
gi|55742559 - ref|NP_998626.1| Rho GDP dissociation inhibitor (GDI) alpha [Danio rerio]
319.0 [0..1] [204..1]

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Predicted Domain #1
Region A:
Residues: [1-204]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEQEPTAEQ LAQIAAENEE DEHSVNYKPP AQKSIQEIQE LDKDDESLRK YKEALLGRVA  60
   61 VSADPNVPNV IVTRLTLVCS TAPGPLELDL TGDLESFKKQ SFVLKEGVEY RIKISFRVNR 120
  121 EIVSGMKYIQ HTYRKGVKID KTDYMVGSYG PRAEEYEFLT PMEEAPKGML ARGSYNIKSR 180
  181 FTDDDKTDHL SWEWNLTIKK EWKD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.30103
Match: 1doaB
Description: Rho GDP-dissociation inhibitor 1, RhoGDI
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 4.21900602727099 bayes_pls_golite062009
cytoskeletal protein binding 3.82728537491772 bayes_pls_golite062009
voltage-gated cation channel activity 2.79599274364249 bayes_pls_golite062009
voltage-gated ion channel activity 2.7120102542099 bayes_pls_golite062009
voltage-gated channel activity 2.70863932585459 bayes_pls_golite062009
potassium channel activity 2.69685666968196 bayes_pls_golite062009
voltage-gated potassium channel activity 2.69627305312298 bayes_pls_golite062009
binding 2.65544526722793 bayes_pls_golite062009
cation channel activity 2.65302958856525 bayes_pls_golite062009
gated channel activity 2.52278796517374 bayes_pls_golite062009
transporter activity 2.46466249895824 bayes_pls_golite062009
substrate-specific transporter activity 2.37642404692102 bayes_pls_golite062009
transmembrane transporter activity 2.37262306131842 bayes_pls_golite062009
substrate-specific channel activity 2.32502571419352 bayes_pls_golite062009
channel activity 2.3181005726144 bayes_pls_golite062009
passive transmembrane transporter activity 2.3181005726144 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.31677709260544 bayes_pls_golite062009
ion transmembrane transporter activity 2.28077016868353 bayes_pls_golite062009
ion channel activity 2.2553711462771 bayes_pls_golite062009
cation transmembrane transporter activity 2.23522391314947 bayes_pls_golite062009
metal ion transmembrane transporter activity 2.15379228421204 bayes_pls_golite062009
inward rectifier potassium channel activity 1.86598930407084 bayes_pls_golite062009
ligand-gated ion channel activity 1.81486809950722 bayes_pls_golite062009
ligand-gated channel activity 1.81486809950722 bayes_pls_golite062009
Rho GDP-dissociation inhibitor activity 1.67374100547551 bayes_pls_golite062009
actin filament binding 1.67203076960313 bayes_pls_golite062009
small GTPase regulator activity 1.55727555528218 bayes_pls_golite062009
protein binding 1.50286160643298 bayes_pls_golite062009
GTPase regulator activity 1.44225801859996 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 1.42486878565247 bayes_pls_golite062009
clathrin binding 1.23902179002817 bayes_pls_golite062009
molecular transducer activity 1.12993648323166 bayes_pls_golite062009
signal transducer activity 1.12993648323166 bayes_pls_golite062009
enzyme regulator activity 1.05880190577068 bayes_pls_golite062009
GDP-dissociation inhibitor activity 0.580608094701522 bayes_pls_golite062009

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