| Protein: | FBpp0307249, gp2... |
| Organism: | Drosophila melanogaster |
| Length: | 1876 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0307249, gp2....
| Description | E-value | Query Range |
Subject Range |
|
|
1068.0 | [0..1] | [1876..2] |
|
Region A: Residues: [1-162] |
1 11 21 31 41 51
| | | | | |
1 MDSILCMILL ILVRNHASEA ARLNHPRVLL PIFEDKAINF TLEVDEPNCY KWSSSRQDLI 60
61 SVMPIYKGFS ECAYQAVVTV RTHDRRRNTA IVFAEEVQTG ETLRSDVIVD VIASLNVRTA 120
121 TRQLYLEEAP AMFELHAFDE QGNEFFTLEG IEFDWEILEP GS
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [163-312] |
1 11 21 31 41 51
| | | | | |
1 KRPTAMRYLT FTDSPYHTVP PTIEKFEADG KKGHMILLEG INTGTAKVTI AMPQAEYKHV 60
61 RPVEVYISVL ANIIIEPSEV TIMAGDSVSF RILQLKMDRL HVIDNNQYYL EVEDSSIAYL 120
121 RGNSATGAAL GRTQVFLRDR NMADSDEVQK
|
| Detection Method: | |
| Confidence: | 1.01 |
| Match: | 1wgoA |
| Description: | Solution structure of the PKD domain from human VPS10 domain-containing receptor SorCS2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cation channel activity | 2.380795199031 | bayes_pls_golite062009 |
| ion channel activity | 2.36513977343491 | bayes_pls_golite062009 |
| substrate-specific channel activity | 2.35358414318244 | bayes_pls_golite062009 |
| channel activity | 2.33902116013883 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 2.33902116013883 | bayes_pls_golite062009 |
| binding | 1.78379749348767 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 1.42148650111845 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.37786160681876 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 1.05846900449968 | bayes_pls_golite062009 |
| neurotransmitter binding | 1.01000297027016 | bayes_pls_golite062009 |
| protein binding | 0.957095895311284 | bayes_pls_golite062009 |
| receptor activity | 0.834057250935552 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.734763306678116 | bayes_pls_golite062009 |
| peptide receptor activity, G-protein coupled | 0.58343455796775 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.581164735940737 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.572165587163775 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.385754568957211 | bayes_pls_golite062009 |
| peptide receptor activity | 0.35906601287757 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.312227316784421 | bayes_pls_golite062009 |
| molecular transducer activity | 0.271680773494877 | bayes_pls_golite062009 |
| signal transducer activity | 0.271680773494877 | bayes_pls_golite062009 |
| neuropeptide binding | 0.119629506661135 | bayes_pls_golite062009 |
| neuropeptide receptor activity | 0.119629506661135 | bayes_pls_golite062009 |
|
Region A: Residues: [313-517] |
1 11 21 31 41 51
| | | | | |
1 GPSALLTVAY PNRLSISLLP HLNWVTVQGE HHAIALDLFA ADGQKITMGT KYSINSEVDE 60
61 SFFAIVDRTR NGSRLFGQAK KEGITQVYGS YKDLSVQAEL QIFEELQLAP TKVVLPYDPN 120
121 SLKPLKLQFH ASGGDNNYAW FSGNPQVIQI DTQGQATTEI RDVKSAYVNQ EVLKDGGKLT 180
181 AHTTVKVALS KNQKISRVAH IYFLP
|
| Detection Method: | |
| Confidence: | 7.69897 |
| Match: | 1f00I |
| Description: | Intimin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [518-1274] |
1 11 21 31 41 51
| | | | | |
1 PERLQITRSN FETALKDFVH VHVGVYARIN NSEVPYTSCD NLHFQLDFSQ PILQLEGNEG 60
61 AEAAHEACHV LRLRATAVGT TSLRVSYMYM DKVLYDIIDL YVFEPLVVLN PIENEVVLPV 120
121 GSSRNIIYAN GPQRSFTVAA EIIQSTAFDE KILKVSKLEF DTQNLITAFT VLCRELGETQ 180
181 FTYRVHNSLP TSSFALYQSE VTTKVHCVRP RFLKLYARHN LRDSCPLEKR TSLLFLKDPE 240
241 NKIEIEIEVH DSNNRRLMNI SSLGLDWEFS AGEERYQKNI IPHRQISELE FNHGVTLPSR 300
301 DLLVLTLSEV ATNFRIKGTV SQYNDKLLAQ HGIHAERPPF GIKNPQTGLI YTPLIENEIR 360
361 LHAVNSTLLP KDYMSIFLAS GYSERIPIAQ GSGYLQLELS EAGIVQVEYN ENTRILVLTP 420
421 LRLGHVRLEL TDRCLMNEPS HLSISVVGIG AIEVVSMDRL ERTTRIEAIV RLFDTNDNLL 480
481 LVDQSKLSAY DLSEVVADQS ILSVRLGEQE NVGPGEIRYT ITGNQVGETK ILFQSGKGIY 540
541 KVASDPLNIQ VFAPIRLFPR DSTLVVGSSI QVYFHGGPHP NTNMIISVEK EQVATISSTV 600
601 VTAHKLGTTK IVGKCLLKNP VTGKDEVVSQ DSVEVHVVAL KGVQIRTPLV RIHSGAVMPA 660
661 TLWGLSDLSP MILGTLQNTK ISWKVSQPQV VEIFNVFTTA GIEYQSGDLI SVRVRALNPG 720
721 KATITASVTL ADGTILPPAT VDLQVFKTLE LVTPNAI
|
| Detection Method: | |
| Confidence: | 1.01 |
| Match: | 1g0dA |
| Description: | Transglutaminase N-terminal domain; Transglutaminase, two C-terminal domains; Transglutaminase catalytic domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| gated channel activity | 3.3185201579574 | bayes_pls_golite062009 |
| ligand-gated channel activity | 3.30263392934988 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 3.30263392934988 | bayes_pls_golite062009 |
| cation channel activity | 3.28214640157037 | bayes_pls_golite062009 |
| ion channel activity | 3.25782775223703 | bayes_pls_golite062009 |
| substrate-specific channel activity | 3.23851263243433 | bayes_pls_golite062009 |
| channel activity | 3.22076385789474 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 3.22076385789474 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 2.67303078740527 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 2.56720911382569 | bayes_pls_golite062009 |
| voltage-gated channel activity | 2.54478612275599 | bayes_pls_golite062009 |
| potassium channel activity | 2.30131005757214 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 2.29930986392959 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 2.27062981227086 | bayes_pls_golite062009 |
| inward rectifier potassium channel activity | 1.59649295659268 | bayes_pls_golite062009 |
| binding | 1.44450711260306 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 1.31347247386931 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 1.28899863735689 | bayes_pls_golite062009 |
| protein binding | 0.815393107558824 | bayes_pls_golite062009 |
| cysteine-type peptidase activity | 0.313867925041617 | bayes_pls_golite062009 |
| signal transducer activity | 0.0317806731782007 | bayes_pls_golite062009 |
| molecular transducer activity | 0.0317806731782007 | bayes_pls_golite062009 |
|
Region A: Residues: [1275-1474] |
1 11 21 31 41 51
| | | | | |
1 KMDSILAAPR SILQLKSNMD NVVYKLDDRS NGIVSVTPDG LVHTKDSLGR DLIIATTADQ 60
61 SLPIGIEVKN VQYILVTLMP ILKLRELEHK IPRGMNFVFK VSLHDNLGNE LSHNIEDFNG 120
121 LRYELGNKDD VDVQIDNNLT FALNLMRETN NVIGISLKDS TGVKHSMDFI KLSVVESDNL 180
181 FPTKTIFSVG DIICFDSPLT
|
| Detection Method: | |
| Confidence: | 0.998 |
| Match: | 2ec8A |
| Description: | No description for 2ec8A was found. |
|
Region A: Residues: [1475-1599] |
1 11 21 31 41 51
| | | | | |
1 LSSTWRSSNE QIVYINKHTG IAQVLSHRLK PGEKIEITNG DETKRGGFLK YDLEVRESDT 60
61 ILFVKSVDTF SGPEYRGQLV IRNHLQSEKY SNLIAQNVSK CARELGSVPV NFFTCRLAAK 120
121 DALGR
|
| Detection Method: | |
| Confidence: | 1.23 |
| Match: | 1e07A |
| Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1600-1663] |
1 11 21 31 41 51
| | | | | |
1 NLLKMYKVDA LFEPSIGQYS CRLQLLTGFI ELLSIVKTHD VYLELEAVVA KGVSDKMSLK 60
61 LVPG
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1664-1876] |
1 11 21 31 41 51
| | | | | |
1 IKVFPESVRV TDLKPHEIHI SGLDKALLKV QVKPSDSKYF AVDFIEHGHG LSKYRLELFD 60
61 DLPLDENFYI LVVSPDTKQS IEVPIIGNTM LAPKCTDRRY GGPLVYRILE NLGFVLTTTV 120
121 IVIISIWVYM SCFQTQGVTQ VNFEAFKKGK SRTELMQQSG RSSQDDTFGD SFNVRNFSPD 180
181 RRRPPSNALS ESYIYGHPRL NSSNRSENST SFS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
