| Protein: | cos-PA, FBpp0307854 |
| Organism: | Drosophila melanogaster |
| Length: | 1201 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cos-PA, FBpp0307854.
| Description | E-value | Query Range |
Subject Range |
|
|
362.0 | [0..92] | [1187..12] |
|
Region A: Residues: [1-90] |
1 11 21 31 41 51
| | | | | |
1 MEIPIQVAVR IFPHRELKDL LRSFGPTEPK KDAQAVDEGA DSKDSEAQVP AAEKDNPSIS 60
61 ETDPNGNAEQ DSAADSKTIP DANGNDSGQK
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [91-408] |
1 11 21 31 41 51
| | | | | |
1 DYPDSAYCVQ AIPISASALG LPSALPGGDP MDSIAAGLIQ VGPHTVPVTH ALPSSSSQEQ 60
61 VYHQTVFPLI TLFLEGFDAS VVTYGQRGQG KSYTLYGNVQ DPTLTDSTEG VVQLCVRDIF 120
121 SHISLHPERT YAINVGFVEI CGGDVCDLLG MGNIHCTNVD AVFHWLQVGL SARQSLPAHT 180
181 LFTLTLEQQW VSKEGLLQHR LSTASFSDLC GTERCGDQPP GRPLDAGLCM LEQVISTLTD 240
241 PGLMYGVNGN IPYGQTTLTT LLKDSFGGRA QTLVILCVSP LEEHLPETLG NLQFAFKVQC 300
301 VRNFVIMNTY SDDNTMIV
|
| Detection Method: | |
| Confidence: | 87.30103 |
| Match: | 1gojA |
| Description: | Kinesin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| microtubule motor activity | 7.68336791348661 | bayes_pls_golite062009 |
| plus-end-directed microtubule motor activity | 4.97507344344589 | bayes_pls_golite062009 |
| motor activity | 4.04927796049806 | bayes_pls_golite062009 |
| transporter activity | 3.10463051760206 | bayes_pls_golite062009 |
| transmembrane transporter activity | 2.95886887664984 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 2.95079405147356 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.87427509025394 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 2.85499564954033 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 2.85178667290149 | bayes_pls_golite062009 |
| smoothened binding | 2.78675393035288 | bayes_pls_golite062009 |
| tubulin binding | 2.67743463093593 | bayes_pls_golite062009 |
| microtubule binding | 2.59155206524122 | bayes_pls_golite062009 |
| hydrolase activity | 2.55157966585974 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 2.50494515048649 | bayes_pls_golite062009 |
| primary active transmembrane transporter activity | 2.39629638016861 | bayes_pls_golite062009 |
| P-P-bond-hydrolysis-driven transmembrane transporter activity | 2.39600931083427 | bayes_pls_golite062009 |
| ATPase activity | 2.39535714892224 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 2.36051733655256 | bayes_pls_golite062009 |
| ATPase activity, coupled to movement of substances | 2.35906629925754 | bayes_pls_golite062009 |
| ATPase activity, coupled to transmembrane movement of substances | 2.35679406876731 | bayes_pls_golite062009 |
| ATPase activity, coupled | 2.24901251684901 | bayes_pls_golite062009 |
| binding | 2.21604035604783 | bayes_pls_golite062009 |
| protein transporter activity | 1.71214667007262 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.65609907941094 | bayes_pls_golite062009 |
| nucleic acid binding | 1.6268310953221 | bayes_pls_golite062009 |
| DNA binding | 1.52986172845338 | bayes_pls_golite062009 |
| transcription regulator activity | 1.49328374516529 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 1.3182108176243 | bayes_pls_golite062009 |
| microfilament motor activity | 1.28029120876672 | bayes_pls_golite062009 |
| protein binding | 1.22129154759482 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.990232056623698 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.929901285538132 | bayes_pls_golite062009 |
| nucleotide binding | 0.922442819194247 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.920987930180051 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.920926158369519 | bayes_pls_golite062009 |
| GTPase activity | 0.83849854735032 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.704934361725919 | bayes_pls_golite062009 |
| molecular transducer activity | 0.683309012097319 | bayes_pls_golite062009 |
| signal transducer activity | 0.683309012097319 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.661834961742057 | bayes_pls_golite062009 |
| receptor activity | 0.633514002718998 | bayes_pls_golite062009 |
| guanyl nucleotide binding | 0.58271536409458 | bayes_pls_golite062009 |
| GTP binding | 0.5687070753098 | bayes_pls_golite062009 |
| guanyl ribonucleotide binding | 0.54474544621658 | bayes_pls_golite062009 |
| ATP binding | 0.41092997612902 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 0.385813421701492 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 0.377870145186619 | bayes_pls_golite062009 |
| actin-dependent ATPase activity | 0.36110509588725 | bayes_pls_golite062009 |
| transcription factor activity | 0.342904707338268 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.282397764628576 | bayes_pls_golite062009 |
| signal recognition particle binding | 0.20866768220789 | bayes_pls_golite062009 |
| structural constituent of ribosome | 0.208665086324262 | bayes_pls_golite062009 |
| minus-end-directed microtubule motor activity | 0.068779631341469 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.028319099023125 | bayes_pls_golite062009 |
|
Region A: Residues: [409-507] |
1 11 21 31 41 51
| | | | | |
1 QPAEPVPESN SSAGPLSQAG PGDNFGLQFA ASQWSKLVTN AEGLFSKLID SKLITEVEKE 60
61 QIEEWLFLKQ ECEECLSSTE AMRQQKQLVP ILEAEEPED
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [508-1201] |
1 11 21 31 41 51
| | | | | |
1 VNSEAANSES PNSDNENDTD NESHRPDLDD KIESLMEEFR DKTDALILEK HAEYLSKHPK 60
61 AVMQSQDREI EAQPPEENGD DRKVSIGSRR RSVQPGASLS TAELAMLNRV ASQQPPPPID 120
121 PESVVDPLES SSGEGIRQAA LAAAAATAPI EQLQKKLRKL VAEIEGKQRQ LREIEETIQV 180
181 KQNIIAELVK NSDTRSHAKQ RFHKKRAKLE AECDKAKKQL GKALVQGRDQ SEIERWTTII 240
241 GHLERRLEDL SSMKHIAGES GQKVKKLQQS VGESRKQADD LQKKLRKECK LRCQMEAELA 300
301 KLRESRETGK ELVKAQGSPE QQGRQLKAVQ ARITHLNHIL REKSDNLEEQ PGPEQQETLR 360
361 HEIRNLRGTR DLLLEERCHL DRKLKRDKVL TQKEERKLLE CDEAIEAIDA AIEFKNEMIT 420
421 GHRSIDTSDR IQREKGEQML MARLNRLSTE EMRTLLYKYF TKVIDLRDSS RKLELQLVQL 480
481 ERERDAWEWK ERVLSNAVRQ ARLEGERNAV LLQRQHEMKL TLMLRHMAEE TSASSASYGE 540
541 RALAPACVAP PVQASSDFDY DHFYKGGGNP SKALIKAPKP MPTGSALDKY KDKEQRSGRN 600
601 IFAKFHVLTR YASAAAAGSS GSTAEESTAL IESTTTATAT TTSTTTTGAV GKVKDKALVS 660
661 FRPEQLKRLM PAPTATKVTR QKNKIIIQDA SRRN
|
| Detection Method: | |
| Confidence: | 14.522879 |
| Match: | 1i84S |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
