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View Structure Prediction Details

Protein: dgo-PA, dgo-PB
Organism: Drosophila melanogaster
Length: 927 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dgo-PA, dgo-PB.

Description E-value Query
Range
Subject
Range
gi|115609690 - gi|115609690|ref|XP_001184628.1| PREDICTED: similar to ankyrin 2,3/unc44 [Strongylocentrotus purpura...
665.0 [0..2] [633..79]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQHGSSRIPK QEALPNAISG PDSSNWTSLH EAVAAGDDRR VEGLLFSNAD RLARESVQGN  60
   61 TPLHEAASRG FSRCVKLICT PPTPPASSGV GK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.0
Match: 1wdyA
Description: Crystal structure of ribonuclease
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [93-560]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAKGQKDKDK DKNKGRVKVA HQTIEALHNS ALGIANNEGL SALHLAAQNG HNQSSRELLL  60
   61 AGADPDVRNN YGDTPLHTAC RYGHAGVSRI LLSALCDPNK TNLNGDTALH ITCAMGRRKL 120
  121 TRILLEADAR LGIKNAQGDC PMHIAIRKNY REIIEILNTP KKIRNRKEKP KEGGSRSDKD 180
  181 RDRERDVVDK GINWSPYGCH YFPDPRAFPS PKLETLPKEP LKSGEQYFLD LAGHIHKGPV 240
  241 SVGNTCYCGP FFRHIENKLN CNRKSLKKYV HKTKERLGHK VQALAIKTND QIEQLTRTMI 300
  301 EDRLRCESKR QHLSEFLRRG EPMRSTFDQQ NKSSRIERTM SRCRSLELLE NNHEGGRLTN 360
  361 SRSVDVLEDQ AVEAIVHRSA EVQVDSDSDD DSNEARDEEE AEVGDKDQVQ EEAEPEEHSK 420
  421 LDELKLDFLK VSERLGVLLE KTTLIMERDS EQESKRQLSS LSPPYNPH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 103.0
Match: 1n11A
Description: Ankyrin-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.98134935593201 bayes_pls_golite062009
cytoskeletal protein binding 1.93050618316228 bayes_pls_golite062009
protein binding 1.54890102798695 bayes_pls_golite062009
structural constituent of cytoskeleton 1.29094941611102 bayes_pls_golite062009
structural molecule activity 0.808967137205604 bayes_pls_golite062009
enzyme binding 0.60140077251711 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.592443052058176 bayes_pls_golite062009
small conjugating protein ligase activity 0.529085233093928 bayes_pls_golite062009
actin binding 0.168912685840912 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [561-689]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRAESAQLRE DKESVNSPNF DEYANVIRRY PNSSETSNPS QNSNSWDWEA SPTGSNPHPD  60
   61 YNKYYQRIGR GENMLNSVIK ALRKDASFAD LGKEETAVNE TAEGMGGDKL LYKEQASEAA 120
  121 GISNLMKRQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [690-927]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLCLEDNYPV MSNLFYSNPI MEYAEETEVR QNGNESMSKV EIRNSEIKCL KKPNAGQVRD  60
   61 MVAQLQNTID SNRQDSQTAH VIAARSHSRL NNNFHHLEGT SSNPSPTYSI PHRSSAQFGL 120
  121 PERHIPKDAY FHELPHRPPI PQTPQRRLHS GYVPNASLYR SEDLYVGRIP HPNAPPRQVD 180
  181 YVDAVAYRPL QSPTFQAIVP PHVNQRPRNW PHPNLPSNEI DLDELSAVGL YNNVSSLV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle