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View Structure Prediction Details

Protein: MCPH1-PB
Organism: Drosophila melanogaster
Length: 826 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCPH1-PB.

Description E-value Query
Range
Subject
Range
gi|70878483 - gi|70878483|gb|EAN91735.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71649745 - gi|71649745|ref|XP_813586.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
327.0 [0..7] [823..771]

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Predicted Domain #1
Region A:
Residues: [1-111]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKFLLRNPT WKTKTYGSVV ASSAAAAKKT AASSTRRPLH DSNLGDFRSK AAAPSPKSLS  60
   61 QAPADDQAAR DRLMLKPALA VSKAISQHRS EFHQDENEAG AEGSAAKPDP P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [112-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGAATPTRQE GHWARLQQDL NSPNAALRLR AIRALKSPTK SAYNTFDVPL AEQSIITMEE  60
   61 RNPQEPPSLP ELLKDIVVYV EVRTGNDNRS EGVKSIIAKM GAQVKDRLTR TTTHVVFKDG 120
  121 LLSTYKKATE WNIPVVSILW IEACKVQLKI CDPKQFPISN IRMYEYPELF GKMPRVKFMQ 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.99
Match: 2d8mA
Description: No description for 2d8mA was found.

Predicted Domain #3
Region A:
Residues: [292-517]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDSELNQRPR KRQGTPTSSK DNEPGSTNKR AQTGTPTTTT PKNDISRFFR AINHNKPSDD  60
   61 EAIESPATKL LNRISSGCYT PLPAGGTPQL MGTNGSGDAV AQKVQAQKSL QFGEQTDSNT 120
  121 PQAKPSSTSR PRRSTVDPPP VMTPPVRTTR RRSCVAEISS PAATDTRMTR RRSSLLTSTV 180
  181 IHEADPTQTA VAEPRMTRRR SSLLGIAKQA EETAQRQTIQ PITEEL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [518-697]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APVEENRNSI IMAETNIINN TNCLEQSIEI TAVEAEASFK ADRRGTLYAS ELMDISSPRR  60
   61 RSVAKSSLEL RQENLAPRAR QSLSNVTTQT SFLDVEQQVT PLFSSTRLPT GQTTGNRRRT 120
  121 IFNMDMDVIN ESIERMNQSH RMSLALANKA ELGESCQVHE QEPPQAEPVP SQEPKRRRLF 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [698-826]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPNDEVVISP AMSNRKSRLS ITGSGSSSSV QKRRRSLATP AKSSSSELCA TTPLSKAVTN  60
   61 KEAEKSKSNT EISEASLDAV PEVKKSTSNA GEENEKPKGK SRTRIRTLVH TNMHQEQINV 120
  121 IRKVGNTTE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle