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View Structure Prediction Details

Protein: CG8494-PA
Organism: Drosophila melanogaster
Length: 975 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG8494-PA.

Description E-value Query
Range
Subject
Range
gi|21429716 - gi|21429716|gb|AAM50536.1| AT06247p [Drosophila melanogaster]
689.0 [0..1] [975..16]

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Predicted Domain #1
Region A:
Residues: [1-242]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSSNPNPH NPYVEHRNRT IHSSQGHTLA NGYAMGDPRS SRCHDKLFSG SLKSLARRED  60
   61 SNASDSEGTD TAKGSGTGLV GLQNIANTCY MNSALQALSN LPPMTHYFIN CSDLVEYIAE 120
  121 QSARRCKPGG LAKSYRRLMQ EIWQDVDDPK EFIAPRGILY GIRTVHPMFR GYQQHDTQEF 180
  181 LRCFMDQLHE ELTEQVSMLP QTQNQPQYQS LQQQQPSETD DENDDEAAPA SLSHASESEY 240
  241 DT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.0
Match: 1vjvA
Description: Crystal structure of Ubiquitin carboxyl-terminal hydrolase 6 (yfr010w) from Saccharomyces cerevisiae at 1.74 A resolution
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [243-552]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CESSMSERSA EVLLKTEYFV TPCRTNGSNS GLPEGHSVQL QQAPLQHQQK NASSAEQKPI  60
   61 EAARSIISDV FDGKLLSSVQ CLTCDRVSTR EETFQDLSLP IPNRDFLNVL HQTHSLSVQS 120
  121 LNAAETSART NEGWLSWMWN MLRSWIYGPS VTLYDCMASF FSADELKGDN MYSCERCNKL 180
  181 RTGIKYSRVL TLPEVLCIHL KRFRNDLSYS SKISSDVYFP LEGFDMRPYI HKDCKSEVAI 240
  241 YNLSSVICHH GTVGGGHYTC FARNTLNGKW YEFDDQFVTE VSSELVQSCQ AYVLFYHKHN 300
  301 PQMKLVRDEA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.30103
Match: 2gfoA
Description: No description for 2gfoA was found.

Predicted Domain #3
Region A:
Residues: [553-635]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLSTSHPLC DSDIQFYITR EWLSRLATFS EPGPINNQEM LCPHGGILHS KADVISQIAV  60
   61 PISQPLWDYL YRTFGGGPAV NII

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.88
Match: 1w6vA
Description: Solution structure of the DUSP domain of hUSP15
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.15365778232348 bayes_pls_golite062009
protein binding 1.01235094804751 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [636-779]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FECEICKRAA ETLSRRQQYE LNEFTKYNGL QNEFDSTAIY AIAMPWLRSW QQFSRGKTHK  60
   61 DPGPITNEGI AAPTENGSAT VSCVRLGSDY AQLNARLWRF LHNIYGGGPE IILRQALSDE 120
  121 DDAEEIEIID QDDECDDDED QDLE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.221849
Match: 1w6vA
Description: Solution structure of the DUSP domain of hUSP15
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.25618438147954 bayes_pls_golite062009
protein binding 1.14865467626428 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [780-975]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEGEDEEIAA ASYQHNHSDT ESNLGIRNTP SPSPSTSPSP SLTGTRQPME TESDLRPSSS  60
   61 KSKRSRSKMK VSALRLNMRN RGKRNRSAFK QYAEMFGAKG NYNAHSNAEP VVSEKDEKDK 120
  121 DNDRTVAFPS EYSLPISIPF QSDNFQVNGV HEKSRDKGKL RNSSKSGSTA ATKENVTLQK 180
  181 FVTLREANGP SDETDI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle