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View Structure Prediction Details

Protein: Cpsf160-PB
Organism: Drosophila melanogaster
Length: 1420 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Cpsf160-PB.

Description E-value Query
Range
Subject
Range
gi|109480949, gi... - gi|109482490|ref|XP_001075234.1| PREDICTED: similar to cleavage and polyadenylation specific factor ...
1310.0 [0..1] [1420..1]

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Predicted Domain #1
Region A:
Residues: [1-166]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSMCKQTHS ATAVEFSIAC RFFNNLDENL VVAGANVLKV YRIAPNVEAS QRQKLNPSEM  60
   61 RLAPKMRLEC LATYTLYGNV MSLQCVSLAG AMRDALLISF KDAKLSVLQH DPDTFALKTL 120
  121 SLHYFEEDDI RGGWTGRYFV PTVRVDPDSR CAVMLVYGKR LVVLPF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [167-236]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKDNSLDEIE LADVKPIKKA PTAMVSRTPI MASYLIALRD LDEKIDNVLD IQFLHGYYEP  60
   61 TLLILYEPVR 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [237-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TCPGRIKVYP IQKPIGGCLV MTVNAVIYLN QSVPPYGVSL NSSADNSTAF PLKPQDGVRI  60
   61 SLDCANFAFI DVDKLVISLR TGDLYVLTLC VDSMRTVRNF HFHKAAASVL TSCICVLHSE 120
  121 YIFLGSRLGN SLLLHFTEED QSTVITLDEV 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [387-722]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQQSEQQQRN LQDEDQNLEE IFDVDQLEMA PTQAKSRRIE DEELEVYGSG AKASVLQLRK  60
   61 FIFEVCDSLM NVAPINYMCA GERVEFEEDG VTLRPHAESL QDLKIELVAA TGHSKNGALS 120
  121 VFVNCINPQI ITSFELDGCL DVWTVFDDAT KKSSRNDQHD FMLLSQRNST LVLQTGQEIN 180
  181 EIENTGFTVN QPTIFVGNLG QQRFIVQVTT RHVRLLQGTR LIQNVPIDVG SPVVQVSIAD 240
  241 PYVCLRVLNG QVITLALRET RGTPRLAINK HTISSSPAVV AISAYKDLSG LFTVKGDDIN 300
  301 LTGSSNSAFG HSFGGYMKAE PNMKVEDEED LLYGDA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.09691
Match: 2b5nA
Description: Crystal Structure of the DDB1 BPB Domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [723-1420]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSAFKMNSMA DLAKQSKQKN SDWWRRLLVQ AKPSYWLVVA RQSGTLEIYS MPDMKLVYLV  60
   61 NDVGNGSMVL TDAMEFVPIS LTTQENSKAG IVQACMPQHA NSPLPLELSV IGLGLNGERP 120
  121 LLLVRTRVEL LIYQVFRYPK GHLKIRFRKM DQLNLLDQQP THIDLDENDE QEEIESYQMQ 180
  181 PKYVQKLRPF ANVGGLSGVM VCGVNPCFVF LTFRGELRIH RLLGNGDVRS FAAFNNVNIP 240
  241 NGFLYFDTTY ELKISVLPSY LSYDSVWPVR KVPLRCTPRQ LVYHRENRVY CLITQTEEPM 300
  301 TKYYRFNGED KELSEESRGE RFIYPIGSQF EMVLISPETW EIVPDASITF EPWEHVTAFK 360
  361 IVKLSYEGTR SGLKEYLCIG TNFNYSEDIT SRGNIHIYDI IEVVPEPGKP MTKFKIKEIF 420
  421 KKEQKGPVSA ISDVLGFLVT GLGQKIYIWQ LRDGDLIGVA FIDTNIYVHQ IITVKSLIFI 480
  481 ADVYKSISLL RFQEEYRTLS LASRDFNPLE VYGIEFMVDN SNLGFLVTDA ERNIIVYMYQ 540
  541 PEARESLGGQ KLLRKADYHL GQVVNTMFRV QCHQKGLHQR QPFLYENKHF VVYGTLDGAL 600
  601 GYCLPLPEKV YRRFLMLQNV LLSYQEHLCG LNPKEYRTLK SSKKQGINPS RCIIDGDLIW 660
  661 SYRLMANSER NEVAKKIGTR TEEILGDLLE IERLASVF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 151.0
Match: 2b5lA
Description: Crystal Structure of DDB1 In Complex with Simian Virus 5 V Protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle