YRC Public Data Repository - Protein Structure Prediction

Protein:	Reg-2-PA
Organism:	Drosophila melanogaster
Length:	260 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Reg-2-PA.

Description	E-value	Query Range	Subject Range
gi\|21483246 - gi\|21483246\|gb\|AAM52598.1\| GH02773p [Drosophila melanogaster]	184.0	[0..1]	[260..20]
gi\|125977548\|ref... - GA16604-PA [Drosophila pseudoobscura], GA16604 [Drosophila pseudoobscura pseudoobscura] gi\|125977548, gi... - gi\|54641557\|gb\|EAL30307.1\| GA16604 [Drosophila pseudoobscura pseudoobscura], gi\|125977548\|ref\|XP_001...	177.0	[0..1]	[260..1]
gi\|116127673, gi... - gi\|118785993\|ref\|XP_315052.3\| ENSANGP00000002421 [Anopheles gambiae str. PEST], gi\|116127673\|gb\|EAA1...	156.0	[0..3]	[260..21]
gi\|229811380, gi... - gi\|229845694\|ref\|ZP_04465817.1\| phosphoglycolate phosphatase [Haemophilus influenzae 6P18H1], gi\|229... gi\|144985848, gi... - gi\|145633479\|ref\|ZP_01789208.1\| phosphoglycolate phosphatase [Haemophilus influenzae 3655], gi\|14498... GPH_HAEI8 - Phosphoglycolate phosphatase OS=Haemophilus influenzae (strain 86-028NP) GN=NTHI0697 PE=3 SV=1	148.0	[0..5]	[253..3]
GPH_SHISS - Phosphoglycolate phosphatase OS=Shigella sonnei (strain Ss046) GN=SSON_3516 PE=3 SV=1	147.0	[0..1]	[253..1]
EG11871 - phosphoglycolate phosphatase / Phosphoglycolate phosphatase; in dam operon; involved in degradation ... gi\|194421583, gi... - gi\|83585104\|ref\|ZP_00923756.1\| COG0546: Predicted phosphatases [Escherichia coli 101-1], gi\|19443949... gi\|75211751, gi\|... - gi\|75211751\|ref\|ZP_00711815.1\| COG0546: Predicted phosphatases [Escherichia coli B171], gi\|194426923... gi\|238902476, gi... - gi\|238902476\|ref\|YP_002928272.1\| phosphoglycolate phosphatase [Escherichia coli BW2952], gi\|23886204... gi\|191167879, gi... - gi\|75228961\|ref\|ZP_00715553.1\| COG0546: Predicted phosphatases [Escherichia coli B7A], gi\|191167879\|... gi\|251786638, gi... - gi\|251786638\|ref\|YP_003000942.1\| hypothetical protein B21_03189 [Escherichia coli BL21], gi\|24237891... gi\|193061794, gi... - gi\|75260326\|ref\|ZP_00731594.1\| COG0546: Predicted phosphatases [Escherichia coli E22], gi\|193061794\|... gi\|253771788, gi... - gi\|254290063\|ref\|YP_003055811.1\| phosphoglycolate phosphatase [Escherichia coli BL21(DE3)], gi\|25397... gi\|89110625, gi\|... - gi\|89110625\|ref\|AP_004405.1\| phosphoglycolate phosphatase [Escherichia coli str. K-12 substr. W3110]... gi\|253975214, gi... - gi\|254163313\|ref\|YP_003046421.1\| phosphoglycolate phosphatase [Escherichia coli B str. REL606], gi\|2... GPH_ECOLI - Phosphoglycolate phosphatase (EC 3.1.3.18) (PGPase) (PGP) - Escherichia coli gi\|170082902, gi... - gi\|170082902\|ref\|YP_001732222.1\| phosphoglycolate phosphatase [Escherichia coli str. K-12 substr. DH... EG11871 - phosphoglycolate phosphatase / Phosphoglycolate phosphatase; in dam operon; involved in degradation ...	147.0	[0..1]	[253..1]
gi\|115514777, gi... - gi\|117625653\|ref\|YP_858976.1\| phosphoglycolate phosphatase [Escherichia coli APEC O1], gi\|115514777\|... gi\|91212857, gi\|... - gi\|91212857\|ref\|YP_542843.1\| phosphoglycolate phosphatase [Escherichia coli UTI89], gi\|91074431\|gb\|A... GPH_ECOL6 - Phosphoglycolate phosphatase OS=Escherichia coli O6 GN=c4155 PE=3 SV=1 GPH_ECOL6 - Phosphoglycolate phosphatase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=c4155... gi\|218367211, gi... - gi\|218560442\|ref\|YP_002393355.1\| phosphoglycolate phosphatase [Escherichia coli S88], gi\|218367211\|e... gi\|226902376, gi... - gi\|237703112\|ref\|ZP_04533593.1\| phosphoglycolate phosphatase [Escherichia sp. 3_2_53FAA], gi\|2269023... gi\|227883515, gi... - gi\|227883515\|ref\|ZP_04001320.1\| phosphoglycolate phosphatase [Escherichia coli 83972], gi\|227839394\|...	147.0	[0..1]	[253..1]
gi\|145272121, gi... - gi\|145638526\|ref\|ZP_01794135.1\| phosphoglycolate phosphatase [Haemophilus influenzae PittII], gi\|145... gi\|53733330 - gi\|53733330\|ref\|ZP_00156383.2\| COG0546: Predicted phosphatases [Haemophilus influenzae R2866]	147.0	[0..5]	[253..3]
GPH_HAEIN - Phosphoglycolate phosphatase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) G... GPH_HAEIN - Phosphoglycolate phosphatase OS=Haemophilus influenzae GN=gph PE=3 SV=1	146.0	[0..5]	[253..3]

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Predicted Domain #1

Region A:
Residues: [1-260]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSLSRFRLI TFDVTNTLLQ FRTTPGKQYG EIGALFGARC DNNELAKNFK ANWYKMNRDY  60
   61 PNFGRDTNPQ MEWQQWWRKL IAGTFAESGA AIPDEKLHNF SNHLIELYKT SICWQPCNGS 120
  121 VELLQQLRKE LKPEKCKLGV IANFDPRLPT LLQNTKLDQY LDFAINSYEV QAEKPDPQIF 180
  181 QKAMEKSGLK NLKPEECLHI GDGPTTDYLA AKELGWHSAL VHEKSYAYLV KKYGEDIDRD 240
  241 HVFPSLYDFH KKISDGAVVW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.39794
Match:	2hszA
Description:	No description for 2hszA was found.

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.55296860681783	bayes_pls_golite062009
binding	0.660822867191303	bayes_pls_golite062009
hydrolase activity	0.194960782858734	bayes_pls_golite062009
phosphatase activity	0.0985887286442809	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.0342238658800214	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: