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View Structure Prediction Details

Protein: gi|17737813, gi|...
Organism: Drosophila melanogaster
Length: 554 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|17737813, gi|....

Description E-value Query
Range
Subject
Range
gi|92109990 - gi|92109990|gb|ABE73319.1| IP03519p [Drosophila melanogaster]
475.0 [0..1] [553..16]

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Predicted Domain #1
Region A:
Residues: [1-554]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDFKVQQRR YRTSEKTVVS TTYGPIKGVK RKSIYGQSYF SFERIPFAKP PVGELRYKAP  60
   61 QPPEVWTEVR SCTSQGPKPL QKHFVFEMTD GSEDCLYLNV YTKNLYPTKP MPVMVWIYGG 120
  121 GFQFGEASRE CYSPDYLLRE DVVVISINYR LGPLGFLCLD DPELDVPGNA GLKDQVLALR 180
  181 WVKANCSRFG GDSANITIFG DSAGSASVHY MMITEQTHGL FHKAICMSGN TLSPWAVTPQ 240
  241 RNWPYRLAVQ AGYAGENNTR DVWEFLKNAK GSEIIKANGE LCIDEEKKER IGFSFGPVIE 300
  301 PYVTSHCVVP KKPIEMMRTA WSNNIPLIIG GVSNEGLLLY SETKTNPKCL NELDDCRFVV 360
  361 PIELNMDRES ALCREYGDQL RQCYYGDKTP SLDTLHEYLQ MVSHEYFWFP IYRTVLSRLQ 420
  421 YARSAPTYLY RFDFDSKHFN HLRILSCGKK VRGTCHGDDL SYLFYNSLAR KLKNHTREYK 480
  481 CIERLVGLWT HFAACGNPNF DPEQEDLWQP VDPAAVEKHQ LKCLNISDEL KVIDVPDLKK 540
  541 LMVWESFFRR DELL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 121.0
Match: 1mx1A
Description: Mammalian carboxylesterase (liver carboxylesterase I)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
acetylcholinesterase activity 6.01557374116734 bayes_pls_golite062009
juvenile hormone epoxide hydrolase activity 5.69212503305375 bayes_pls_golite062009
epoxide hydrolase activity 4.54228071084398 bayes_pls_golite062009
ether hydrolase activity 3.98161932704074 bayes_pls_golite062009
cholinesterase activity 3.53190978140684 bayes_pls_golite062009
hydrolase activity, acting on ether bonds 3.22022434415297 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 3.19190626066707 bayes_pls_golite062009
laminin-1 binding 2.61620056180634 bayes_pls_golite062009
choline binding 2.44944581139315 bayes_pls_golite062009
acetylcholine binding 2.15366394064412 bayes_pls_golite062009
carboxylesterase activity 2.10340684157921 bayes_pls_golite062009
lipase activity 1.95656432876646 bayes_pls_golite062009
hydrolase activity 1.89798820741335 bayes_pls_golite062009
palmitoyl-(protein) hydrolase activity 1.63586830236611 bayes_pls_golite062009
catalytic activity 1.39629727416851 bayes_pls_golite062009
binding 0.978846093152455 bayes_pls_golite062009
peptidase activity 0.946698616106528 bayes_pls_golite062009
palmitoyl-CoA hydrolase activity 0.92549140936125 bayes_pls_golite062009
protein binding 0.890384359682543 bayes_pls_golite062009
receptor binding 0.845720597560984 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.786172015267385 bayes_pls_golite062009
serine hydrolase activity 0.527527404338 bayes_pls_golite062009
acylglycerol lipase activity 0.345658974420231 bayes_pls_golite062009
serine-type peptidase activity 0.33062249657108 bayes_pls_golite062009
phospholipase activity 0.1336535306364 bayes_pls_golite062009
triglyceride lipase activity 0.05324087110088 bayes_pls_golite062009

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