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View Structure Prediction Details

Protein: nmdyn-D7-PA
Organism: Drosophila melanogaster
Length: 387 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nmdyn-D7-PA.

Description E-value Query
Range
Subject
Range
NDK7_RAT - Nucleoside diphosphate kinase 7 OS=Rattus norvegicus GN=Nme7 PE=1 SV=1
418.0 [0..1] [387..13]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPAAIPASE RRLAFVAEWF HAEAGIIRTF LITYYVSDKA VEVFDQRNKR TFLRRTKIPE  60
   61 LTQRDFFVGS KINVFGRQFD IVDYADDTTR TNLAKY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [97-245]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKKGFVLLKN NMWTKHLGKF LKTLIDNKIN INQGMMVQFS PKMVTQFLSG KDTTDVSSSV  60
   61 LMNELLAGPA ISLELIGDNV VETIKACAQY KSTEAETPSV KLSPSLEELF ESEEIRYGFY 120
  121 YSDNDNDVEM DLKFISEARH SIIKECVFK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 6.61
Match: 1wkjA
Description: Crystal Structure of Nucleoside Diphosphate Kinase from Thermus thermophilus HB8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleobase, nucleoside, nucleotide kinase activity 6.4448415473479 bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor 5.85502930858634 bayes_pls_golite062009
nucleoside diphosphate kinase activity 4.61067707314941 bayes_pls_golite062009
kinase activity 4.26784564496601 bayes_pls_golite062009
catalytic activity 1.80062327922062 bayes_pls_golite062009
transferase activity 0.96744394416511 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.752351123941402 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [246-387]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTTLAIIKPH SIKDGLLGDI ISEILSNGFR LTAMRMILMA RINCEEFYEV YRGVVPEYIP  60
   61 MVAQLASGVC MCMEIACADP EKKTDREFRN FCGPMDPEIA KLLRPHTLRA KFGKSKVQNA 120
  121 VHCTDLPDDS NLELQYMFKI ID

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.522879
Match: 1jxvA
Description: Nucleoside diphosphate kinases
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleobase, nucleoside, nucleotide kinase activity 7.03061421339491 bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor 6.44414487354776 bayes_pls_golite062009
nucleoside diphosphate kinase activity 5.37425936177415 bayes_pls_golite062009
kinase activity 4.60914087199794 bayes_pls_golite062009
catalytic activity 1.91319552351397 bayes_pls_golite062009
transferase activity 1.21163341858368 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.06719669551075 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle