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View Structure Prediction Details

Protein: rin-PE, FBpp0312...
Organism: Drosophila melanogaster
Length: 690 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rin-PE, FBpp0312....

Description E-value Query
Range
Subject
Range
gi|7739653 - gi|7739653|gb|AAF68949.1|AF231031_1 rasputin [Drosophila melanogaster]
244.0 [0..1] [675..1]

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Predicted Domain #1
Region A:
Residues: [1-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVMDATQSQQ PSPQSVGREF VRQYYTLLNK APNHLHRFYN HNSSYIHGES KLVVGQREIH  60
   61 NRIQQLNFND CHAKISQVDA QATLGNGVVV QVTGELSNDG QPMRRFTQTF VLAAQSPKKY 120
  121 YVHNDIFRYQ DLYI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.522879
Match: 1a2kA
Description: Nuclear transport factor-2 (NTF2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.88422211140837 bayes_pls_golite062009
protein binding 1.34243535208605 bayes_pls_golite062009
protein transporter activity 0.960383711156379 bayes_pls_golite062009
transporter activity 0.55283159394909 bayes_pls_golite062009
RNA binding 0.541310012083998 bayes_pls_golite062009
Ran GTPase binding 0.437541267934309 bayes_pls_golite062009
small GTPase binding 0.16703540602196 bayes_pls_golite062009
GTPase binding 0.15019810567677 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [135-216]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDEQDGESRS ENDEEHDVQV VGGTVDQAVQ VAGDVVAQQP QQQQAPPQPQ AQVVVPQQVA  60
   61 PVAAGGAAPQ QIFYPLPAGA AA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [217-418]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRPVAVLPPA PQAAAVPLPA QFTVPPPQPI QNGVVSHEEL QQQQVLVPPS VSPLVQQQQP  60
   61 TGTPVLPIVP VPSAGFQQSP LVAPQLIQQQ QQQQPAQLPP QQQQQQQPIQ QQQPLQQQQQ 120
  121 PLAEPEEVEV APRQQKPPTP VEDFKTIHEQ QQQEKYEAAK QQQNEPKTYA NLFKSTSSSP 180
  181 SGFVNAALQQ QQQLQQQQQQ QQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [419-597]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SISSNTYNSS SATSGGGNGS QVSYSTTASS YNNSNGNSRL DNGGPLPQRN NSIRNNKGDF  60
   61 EQRRSSNTQQ FGDNQQLFLG NIPHHASEDD LREIFSRFGN VLELRILSKA GNKVPPGMRS 120
  121 PLNYGFITYD DPEAVQKCLA NCPLYFPENS PDGQKLNVEE KKPRVRNDMV PRQQIGGNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.221849
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.00411894202318 bayes_pls_golite062009
RNA binding 2.99069397581023 bayes_pls_golite062009
nucleic acid binding 2.31150433509655 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
mRNA binding 0.505477067109476 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [598-690]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNNNMGRLGG NNGPQSRPMG NNNGSGGGMM RNNAGGNNLR QGGGGGNGAP RLGGGGGFGQ  60
   61 RQDNRTGGGN NQSNGPLRGA GNGQSGGGNY GRR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.02
Match: 1jchA
Description: Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle