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View Structure Prediction Details

Protein: Rpb7-PA
Organism: Drosophila melanogaster
Length: 173 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Rpb7-PA.

Description E-value Query
Range
Subject
Range
gi|78701235, gi|... - gi|78701235|ref|ZP_00865687.1| Polyribonucleotide nucleotidyltransferase [Alkalilimnicola ehrlichei ...
155.0 [0..1] [167..555]

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Predicted Domain #1
Region A:
Residues: [1-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFYHISLEQE ILLHPRYFGP QLLETVKQKL YSEVEGTCTG KYGFVIAVTT IDQIGSGVIQ  60
   61 PGQGFVVYPV KYKAIVFRPF KGEVLDAVVK QINKVGMFAE IGPLSCFISH HSIPADMQFC 120
  121 PNGNPPCYKS KDEDVVISGE DKIRLKIVGT RVDATGIFAI GTLMDDYLGL VSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.0
Match: 2c35B
Description: Subunits Rpb4 and Rpb7 of human RNA polymerase II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA polymerase activity 8.99678434167899 bayes_pls_golite062009
DNA-directed RNA polymerase activity 8.99678434167899 bayes_pls_golite062009
nucleotidyltransferase activity 6.44182740737882 bayes_pls_golite062009
structural constituent of ribosome 5.1118741250402 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.85462508375149 bayes_pls_golite062009
structural molecule activity 4.51553901145182 bayes_pls_golite062009
transferase activity 3.90847350895308 bayes_pls_golite062009
ribonuclease activity 3.83159232224897 bayes_pls_golite062009
DNA binding 3.53568546959418 bayes_pls_golite062009
RNA binding 3.49834780836233 bayes_pls_golite062009
2.80746531284205 bayes_pls_golite062009
nucleic acid binding 2.41557476646435 bayes_pls_golite062009
exoribonuclease activity 2.41262897171619 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 2.38378389593693 bayes_pls_golite062009
transcription regulator activity 2.10110937001387 bayes_pls_golite062009
binding 1.9712766790272 bayes_pls_golite062009
structure-specific DNA binding 1.81524862921454 bayes_pls_golite062009
mRNA binding 1.660993824641 bayes_pls_golite062009
single-stranded DNA binding 1.62996999055328 bayes_pls_golite062009
protein binding 1.55473080522232 bayes_pls_golite062009
translation regulator activity 1.46320772716954 bayes_pls_golite062009
translation factor activity, nucleic acid binding 1.40718318783582 bayes_pls_golite062009
translation initiation factor activity 1.27539679024898 bayes_pls_golite062009
transcription activator activity 1.09079153283893 bayes_pls_golite062009
catalytic activity 1.02941336036162 bayes_pls_golite062009
transcription factor activity 0.937752547283357 bayes_pls_golite062009
sequence-specific DNA binding 0.85691075793641 bayes_pls_golite062009
3'-5'-exoribonuclease activity 0.83268201349295 bayes_pls_golite062009
hydrolase activity 0.724860465280978 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.583085644017496 bayes_pls_golite062009
nuclease activity 0.57381531077345 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 0.474251377131502 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 0.47336621289748 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 0.47336621289748 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.223941674251642 bayes_pls_golite062009

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