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View Structure Prediction Details

Protein: CG4546-PA
Organism: Drosophila melanogaster
Length: 457 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG4546-PA.

Description E-value Query
Range
Subject
Range
gi|195152219, gi... - gi|195152219|ref|XP_002017034.1| GL22076 [Drosophila persimilis], gi|194112091|gb|EDW34134.1| GL2207...
gi|125776388, gi... - gi|54639004|gb|EAL28406.1| GA18246 [Drosophila pseudoobscura pseudoobscura], gi|125776388|ref|XP_001...
gi|54639004|gb|E... - GA18246-PA [Drosophila pseudoobscura], GA18246 [Drosophila pseudoobscura pseudoobscura]
569.0 [0..1] [457..1]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSIESKRVQ YRKYLERAGV IDALSKALIK LYEEQNKPED AIRFVRKFMC ESCPDDAQYD  60
   61 VMKNDLEEAK THISKLEQEL ERLRGQIK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [89-457]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSPEEYQELT TEGYKSLMDD EENVSSLLRK YLTPELLEEY MLVTTPAPVD AYLYDCAVSG  60
   61 FEHHDAPVGI FAADADSYDV FNKLFDPIIK DYHGQMDNEN DVLQKDPDFG NVDEIENLDP 120
  121 ERKYILSARI RLARNIEGLP FFPKLTEKQF IEVEEKVRSA TETMDGELIG SYLTMADIDA 180
  181 ETQAEMVKRH ILFQRGDEKL TTAGCYRFWP TGRGVYHNPA ETFLIWVNRQ DHVHIMSMAQ 240
  241 CGDLGDVYNR LVNGLTELEK TLAFARHPRY GNLTACPTNL GTTLRASVHI RLPLLSKDPD 300
  301 RLLALAEEQQ LQVRGTDGGE LSTVEDGVMD ISNKRKLGFT EFELVKTLQD GVVTLINAEE 360
  361 ELEISGQEG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 144.0
Match: 1m15A
Description: Arginine kinase, N-domain; Arginine kinase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
creatine kinase activity 5.87424995551394 bayes_pls_golite062009
ligase activity 1.87132312522382 bayes_pls_golite062009
kinase activity 1.6369709251542 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.55442882643769 bayes_pls_golite062009
catalytic activity 1.08973967683802 bayes_pls_golite062009
binding 0.996233987521931 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.978825607534211 bayes_pls_golite062009
ammonia ligase activity 0.870745932814662 bayes_pls_golite062009
transferase activity 0.844166655291027 bayes_pls_golite062009
acid-ammonia (or amide) ligase activity 0.525598422874668 bayes_pls_golite062009
protein binding 0.133141177821479 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle