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View Structure Prediction Details

Protein: CG11318-PA
Organism: Drosophila melanogaster
Length: 802 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG11318-PA.

Description E-value Query
Range
Subject
Range
gi|73959349 - gi|73959349|ref|XP_866149.1| PREDICTED: similar to cadherin EGF LAG seven-pass G-type receptor 2 iso...
400.0 [0..13] [801..1634]

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Predicted Domain #1
Region A:
Residues: [1-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFNWCAGLF VVLALVSPIY SACPKENQMC LRNGTFQYCD GEERNSSDEL MQTHLVYCTS  60
   61 MFCEPEEFQH DYITRNHDQT PHQNKWKRAR IGERATLHDV CLLRNGMPVT RECRVKDNRA 120
  121 NWESTEHWDP VVCLRRFREH TISGDLNSLH DDVLEGRRRT NDTQGRREMT GIMRNMFRQR 180
  181 GGNLLPADVH MTGQMFGALM QQDKDATVSV DLVSVCKEIM SCDSKVLRLS AQLNATNSLL 240
  241 SQFESYMDAL PEQLVPKDRC GKVVAKPTSD EAETATTGVE TYNF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.045757
Match: 1n7dA
Description: Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor binding 3.10014156620054 bayes_pls_golite062009
ErbB-3 class receptor binding 2.42594378586851 bayes_pls_golite062009
binding 2.33940742543305 bayes_pls_golite062009
ErbB-2 class receptor binding 2.05600933520723 bayes_pls_golite062009
protein binding 1.97546801934296 bayes_pls_golite062009
signal transducer activity 1.66401431847753 bayes_pls_golite062009
molecular transducer activity 1.66401431847753 bayes_pls_golite062009
growth factor activity 1.21105583076744 bayes_pls_golite062009
epidermal growth factor receptor binding 1.08974638257724 bayes_pls_golite062009
transcription factor binding 0.0635904219837768 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [285-479]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDIGVQALIT GNISVFFANP ECDRITGLAI FSAPGDQRKT SASGFWYRFI RFSEDLAKVK  60
   61 EESNLETAAF LPENLWRQVK SRGATYLIFK VYAHDALFVE TSLQRTRKPR SKVISISIPG 120
  121 LRSNYLSLPL PFLLRNENLR NPDSKAFSIG SGCGYWNYET WSTEGVSTES SSDLLKDAII 180
  181 ECHTNHLTQF AFLVG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [480-802]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSYRANDLGE EILITPINEK VLDIISIVGC SLSLLGILGI FLTAALFKSW RSQASTKVLL  60
   61 HLCLAMCLQM MLFVFLNTDD VSEALVVNGN TVRCVALGAA MQYSILVLFS WMLIIAFLQF 120
  121 QRYVTVIGIE RPPRYILKAA IVAWLLPLVP TLLVALIDPD SYVPSAAQLS TDTGICYPSG 180
  181 YGLIFGVVLP VTLITVCNLV IFVYVFYSIS HSLSQSIHKN EKKMVVKQIR LSIMLFFLLG 240
  241 LTWIFGIFAF MQAGVAFSYL FCITATMQGF VMFIYFVLLD STNRRLWVGL ICPTKMELDV 300
  301 QKRTTELQSM TTSSTNYNSR SHQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.30103
Match: 1f88A
Description: Rhodopsin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle