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View Structure Prediction Details

Protein: gi|7302107, gi|7...
Organism: Drosophila melanogaster
Length: 1844 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7302107, gi|7....

Description E-value Query
Range
Subject
Range
gi|125775470, gi... - gi|54638693|gb|EAL28095.1| GA15167-PA [Drosophila pseudoobscura], gi|125775470|ref|XP_001358952.1| G...
1113.0 [0..56] [1844..1]

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Predicted Domain #1
Region A:
Residues: [1-78]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVQPAEMAE NGRSVPDVTA SPGRAPPGPL PANQMPAMGN QQHHGNQQHH GNQQQHHGNQ  60
   61 HSNHRGQSGS LSNAAGVK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [79-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPVMLQGDFR KVSGISSEIF RQIEAVENDH DPNTAAALEA VERRGEMIVR VLEPRCMGSK  60
   61 QAVDAAHKLM NKADARHTVQ LVEIVKRPGQ TLGLYIREGN GADRTDGVFI SRIALESAVY 120
  121 NSGCLRVGDE ILAVNLVDVT HMSLDDVVII MSIPRRLVLA IRQRRGNRGT GSPGPPTLSR 180
  181 PEQKPPPVVV IKRDLRDEDL DETDRMPRPR SSRDGREMTE SRSRLGLGLN NYSPQSEQLD 240
  241 MYYNTRGGGG GAMGEPPNWG YKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.30103
Match: 1z87A
Description: solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [342-499]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPPPSSVITE QPTKAHAFAP SHAYYQNAGT LESLAEKVHA FYPGQPGGPP VGPSRRMSTG  60
   61 TGNVGLAQQH ARFPRSGSDQ HLPRVEYSDY SNSLGRHSLL RSSLKPGTTG GAPMQVGVGG 120
  121 TLGRYGRYDQ QRAGVSKYGP PSGGAQSLTR RSRPNLDY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [500-740]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSDTEATIGP RPSYYYYNRP AIGSMSRGSG GAGGGVGAAS TAALLAGAAD LNKFNSLPRE  60
   61 RPGTRLQGIR SRMGDRLVDE NDGNTSAPEF DVRRGRDLRQ RITASPSIFT ADEYRAWLRR 120
  121 APSSSAIAEQ MRMTRDMFAQ PRAQRFSCSA ENIHDALRNT ESIYSSRNHI LGTGTLDRNM 180
  181 GLTRPISALP VRSMSSQHIG GAGSIRSPSI RRMRQLLELS AGPASPSGSI LSTGGHQSPA 240
  241 P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [741-880]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPSATLPRPH RQIDINPAEF AKYKLDKPIV DIGGISGMLW IHLLAGRGLR TAPEGAAGTA  60
   61 TQGQTRDLYC VIECDRVHKA RTVVRSGDLQ FDWDESFELD LVGNKQLDVL VYSWDPQHRH 120
  121 KLCYRGAISL SSILRQSPLH 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.522879
Match: 2j59M
Description: No description for 2j59M was found.

Predicted Domain #6
Region A:
Residues: [881-1122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLALKVEPRG TIYIRMRHTD PLALYKRRGL PSLRAGYPTL FGADLETVVN RESKNAPGSA  60
   61 PVPIVLRRCV EEVERRGLDI IGLYRLCGSA TKKRLLREAF ERNSRAVELT PEHVPDINVI 120
  121 TGVLKDYLRE LPEPLFTRCL FQMTVDALAV CLPDDPEGNA KLMLSILDCL PRANRATLVF 180
  181 LLDHLSLVVS NSERNKMSAQ ALATVMGPPL MLHSASAQPG ADIDHAQPIA VLKYLLQIWP 240
  241 QP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.522879
Match: 1xa6A
Description: Crystal Structure of the Human Beta2-Chimaerin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
enzyme regulator activity 0.68732227880003 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.590837939249671 bayes_pls_golite062009
GTPase regulator activity 0.59070509814251 bayes_pls_golite062009
enzyme activator activity 0.53004209819211 bayes_pls_golite062009
GTPase activator activity 0.528693496432149 bayes_pls_golite062009
small GTPase regulator activity 0.10243777232979 bayes_pls_golite062009
Ras GTPase activator activity 0.0454578418356197 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [1123-1183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QAQHQQMAQH MGGAAGAMMG GLVTAGSMSN MAGVASGNTG RRGESTGQRG SKVSALPADR  60
   61 Q

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1184-1342]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLLLQQQAQL MAAGNLLRSS TSVTNILSQG HPQLSATANN HLYQSVVGQL AQSHRALQQA  60
   61 VQQPYQLGGS VGSAIPDPSP LPLPGTPSPG SSSASTGSGS GSGKSTDTIK RGASPVSVKQ 120
  121 VKIVDQPSSP YSIVMKKPPL QKDAPVEITT PTTQADTES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1343-1429]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLGCKESNGT ASRRGNVDFY DTHKTQAKSV VNEESSYSSK YTGSETKKII PGNSSYTPSK  60
   61 ANASGLSGGE DYKAMRNKSS ATSSSSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1430-1637]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQATVLSAGS TATSAPTTSS DDSDDLVSYK SSASTNALLA QSQAMTTSQL MSKYLKREPR  60
   61 VQFTPIKSPE SPSPPGSGDG LPKGTYQLVT PISGSSSKPG ATTGAISKYT TGSVESSINA 120
  121 NSQKLSSPSR LCNSKDSNSR TGTASSTTPA TSMVSTGRRL FDSLASSSSS ETETKTYIGG 180
  181 TTAASGAITT TIYTNDTKNS GSSSSKSG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1638-1844]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGGGSGTGLG AVSGASSETR SFGSTLFGSS GLGNGNGSSH NHSSASPSPF TTTNGNGNHN  60
   61 TMHLYGTLPK NGTSTGAALF GGSANSSSYH SSASGSGAGT ASSSGVSSMT GSTNSYDFYT 120
  121 STSSTVSSSR PFANGGNNYH TLGTYRAQYA ATNPFLDAFD EKPGSNGGNA HGEEKLGADK 180
  181 GHHRAAVMAF QSSGDSKNGS DEYDDIK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle