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View Structure Prediction Details

Protein: sc-PA
Organism: Drosophila melanogaster
Length: 345 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sc-PA.

Description E-value Query
Range
Subject
Range
gi|3618335 - gi|3618335|dbj|BAA33212.1| scute [Drosophila simulans]
226.0 [0..1] [345..1]

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Predicted Domain #1
Region A:
Residues: [1-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNNNNTTKS TTMSSSVLST NETFPTTINS ATKIFRYQHI MPAPSPLIPG GNQNQPAGTM  60
   61 PIKTRKYTPR GMALTRCSES VSSLSPGSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [90-186]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAPYNVDQSQ SVQRRNARER NRVKQVNNSF ARLRQHIPQS IITDLTKGGG RGPHKKISKV  60
   61 DTLRIAVEYI RRLQDLVDDL NGGSNIGANN AVTQLQL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.30103
Match: 1am9A
Description: SREBP-1a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.38658950816179 bayes_pls_golite062009
DNA binding 5.18654839258297 bayes_pls_golite062009
nucleic acid binding 5.05768805749761 bayes_pls_golite062009
transcription factor activity 4.78039531631248 bayes_pls_golite062009
binding 3.81829206350975 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.39500382187264 bayes_pls_golite062009
transcription factor binding 2.61163564741984 bayes_pls_golite062009
transcription activator activity 2.5495467409976 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 2.42306484786159 bayes_pls_golite062009
sequence-specific DNA binding 2.31910036997977 bayes_pls_golite062009
protein binding 1.59929864805879 bayes_pls_golite062009
transcription cofactor activity 1.52770895937238 bayes_pls_golite062009
transcription repressor activity 0.955588849035129 bayes_pls_golite062009
promoter binding 0.8576109846276 bayes_pls_golite062009
transcription corepressor activity 0.801830750183111 bayes_pls_golite062009
transcription coactivator activity 0.3513586903977 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [187-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CLDESSSHSS SSSTCSSSGH NTYYQNTISV SPLQQQQQLQ RQQFNHQPLT ALSLNTNLVG  60
   61 TSVPGGDAGC VSTSKNQQTC HSPTSSFNSS MSFDSGTYEG VPQQISTHLD RLDHLDNELH 120
  121 THSQLQLKFE PYEHFQLDEE DCTPDDEEIL DYISLWQEQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle