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View Structure Prediction Details

Protein: Hexo2-PA
Organism: Drosophila melanogaster
Length: 622 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Hexo2-PA.

Description E-value Query
Range
Subject
Range
gi|125981951|ref... - GA14705-PA [Drosophila pseudoobscura], GA14705 [Drosophila pseudoobscura pseudoobscura]
gi|125981951, gi... - gi|54643291|gb|EAL32035.1| GA14705 [Drosophila pseudoobscura pseudoobscura], gi|125981951|ref|XP_001...
523.0 [0..1] [622..1]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFSGYNRYQ CFCSAVGSLL LLSLLSFAVG AALTRADDVG SDADAGSASR KWLCSRTDIC  60
   61 TAEGEMVAGL QYAPEIFESQ RDCRLSCG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [89-622]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYGAIWPMPT GKECTISHRR VRFDPWKVRF HVVAPGEAAT QFLRETNRLF VSNLLKECIR  60
   61 NCTLETSKQI LVRSTVANES LVLDWPTDES YALVVRTTET ATFVDIQATT VYGARHAFET 120
  121 LSNLVTGSLS NGLLMVTTAN ITDRPAFSHR GVLLDTARNF VPLKFIRSTL DAMAASKLNV 180
  181 LHWHVVDTHS FPLEITRVPE MQRYGAYSSS QTYSRQDALN LVKYARLRGI RILIEIDGPS 240
  241 HAGNGWQWGP AAGLGNMSVC LNQSPWRRFC VQPPCGQLNP LNDHMYAVLK EIFEDVAEVG 300
  301 APEETLHMGG DEVFLPCWNN TDEIRDGMRA RGYDLSEQSF LRLWSQFHQR NLNAWDEINE 360
  361 RMYPGIKEPK SVIIWSSHLT NPRYIETYLP KERFIIQTWV ESQDALNREL LQRGYRLIVS 420
  421 TKNAWYLDHG FWGSTSYYNW RTVYSSGMPV GRSKDQVLGG EVCMWSEYVD QNSLESRIWP 480
  481 RAGAAAERMW SNPKSSALLA QRRFYRYRER LLARGIHADA VIPHWCVLHE GQCL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 130.0
Match: 1o7aA
Description: Human beta-Hexosaminidase B
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, hydrolyzing O-glycosyl compounds 6.26329339735894 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 5.92180849080637 bayes_pls_golite062009
chitinase activity 5.52705867024 bayes_pls_golite062009
galactosidase activity 5.29959220339307 bayes_pls_golite062009
alpha-galactosidase activity 4.85819791163713 bayes_pls_golite062009
hydrolase activity 3.5336140444552 bayes_pls_golite062009
hexosaminidase activity 3.21852337137039 bayes_pls_golite062009
mannosidase activity 2.76650385192253 bayes_pls_golite062009
beta-N-acetylhexosaminidase activity 2.69072465526737 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 2.06059323252952 bayes_pls_golite062009
glucosidase activity 1.92306554001182 bayes_pls_golite062009
catalytic activity 1.85569074294201 bayes_pls_golite062009
alpha-amylase activity 1.42264105957213 bayes_pls_golite062009
amylase activity 1.37652764526134 bayes_pls_golite062009
chitin binding 1.29046765706168 bayes_pls_golite062009
molecular transducer activity 0.934517587656668 bayes_pls_golite062009
signal transducer activity 0.934517587656668 bayes_pls_golite062009
transporter activity 0.882190348056302 bayes_pls_golite062009
beta-mannosidase activity 0.858618539860091 bayes_pls_golite062009
transmembrane transporter activity 0.696239852087965 bayes_pls_golite062009
binding 0.601963252939415 bayes_pls_golite062009
beta-glucuronidase activity 0.55376725638834 bayes_pls_golite062009
alpha-glucosidase activity 0.502835520523619 bayes_pls_golite062009
receptor binding 0.497417763506343 bayes_pls_golite062009
beta-N-acetylglucosaminidase activity 0.489832278458081 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 0.23234868908353 bayes_pls_golite062009
substrate-specific transporter activity 0.223550370855368 bayes_pls_golite062009
carbohydrate binding 0.102788238231918 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 7.36798954279472E-5 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle