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View Structure Prediction Details

Protein: FBpp0311925, CG1...
Organism: Drosophila melanogaster
Length: 340 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0311925, CG1....

Description E-value Query
Range
Subject
Range
gi|73993760 - gi|73993760|ref|XP_543203.2| PREDICTED: similar to cathepsin B preproprotein [Canis familiaris]
297.0 [0..1] [338..82]

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Predicted Domain #1
Region A:
Residues: [1-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLLLLVATA ASVAALTSGE PSLLSDEFIE VVRSKAKTWT VGRNFDASVT EGHIRRLMGV  60
   61 HPDAHKFALP DKREVLGDLY VNSVDELPEE FDSRKQWPNC PTIGEIRDQG SCGSCWAFGA 120
  121 VEAMSDRVCI HSGGKVNFHF SADDLVSCCH TCGFGCNGGF PGAAWSYWTR KGIVSGGPYG 180
  181 SNQGCRPYEI SPCEHHVNGT RPPCAHGGRT PKCSHVCQSG YTVDYAKDKH FGSKSYSVRR 240
  241 NVREIQEEIM TNGPVEGAFT VYEDLILYKD GVYQHEHGKE LGGHAIRILG WGVWGEEKIP 300
  301 YWLIGNSWNT DWGDHGFFRI LRGQDHCGIE SSISAGLPKL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.30103
Match: 1pbhA
Description: CRYSTAL STRUCTURE OF HUMAN RECOMBINANT PROCATHEPSIN B AT 3.2 ANGSTROM RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.90619850296986 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.64381885397949 bayes_pls_golite062009
endopeptidase activity 3.75054525912786 bayes_pls_golite062009
hydrolase activity 3.74079711298952 bayes_pls_golite062009
cysteine-type peptidase activity 2.71117522993364 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.95802900199539 bayes_pls_golite062009
binding 1.49113376575534 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
protein binding 0.874003454509364 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.649171767629235 bayes_pls_golite062009
thiolester hydrolase activity 0.59115205419466 bayes_pls_golite062009
kininogen binding 0.41283715939055 bayes_pls_golite062009
signal transducer activity 0.26868506520228 bayes_pls_golite062009
molecular transducer activity 0.26868506520228 bayes_pls_golite062009
ubiquitin-specific protease activity 0.0101379718864654 bayes_pls_golite062009

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