YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC24H6.10c
Organism:	Schizosaccharomyces pombe
Length:	368 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC24H6.10c.

Description	E-value	Query Range	Subject Range
gi\|73854749, gi\|... - gi\|74311272\|ref\|YP_309691.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella sonnei Ss046], gi...	489.0	[0..20]	[366..6]
gi\|193069560, gi... - gi\|75235771\|ref\|ZP_00719926.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ...	489.0	[0..20]	[366..6]
gi\|75237090, gi\|... - gi\|75237090\|ref\|ZP_00721144.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|110640955, gi... - gi\|110640955\|ref\|YP_668683.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli 536], gi...	488.0	[0..20]	[366..6]
gi\|72608691, gi\|... - gi\|74018758\|ref\|ZP_00689378.1\| Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 1 [Burkholderia ...	488.0	[0..2]	[366..8]
AROG_ECO57 - Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive OS=Escherichia coli O157:H7 GN=aroG PE=3 ... gi\|238859808, gi... - gi\|238900012\|ref\|YP_002925808.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine... EG10079 - 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine repressible / 3-deoxy-D-arabino-... gi\|242376509, gi... - gi\|251784236\|ref\|YP_002998540.1\| hypothetical protein B21_00696 [Escherichia coli BL21], gi\|24237650... gi\|15800463, gi\|... - gi\|15800463\|ref\|NP_286475.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli O157:H7 E... gi\|253976912, gi... - gi\|254287605\|ref\|YP_003053353.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine... AROG_ECOLI - Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (EC 2.5.1.54) (Phospho-2-keto-3-deoxyhept... gi\|253972718, gi... - gi\|254160817\|ref\|YP_003043925.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine... gi\|254591304, gi... - gi\|254791904\|ref\|YP_003076741.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine... gi\|168750246, gi... - gi\|188015532\|gb\|EDU53654.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|1651339, gi\|8... - gi\|89107605\|ref\|AP_001385.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine rep... gi\|13360241, gi\|... - gi\|15830036\|ref\|NP_308809.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli O157:H7 s... gi\|168763344, gi... - gi\|189366448\|gb\|EDU84864.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|168757043, gi... - gi\|189355850\|gb\|EDU74269.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|187768162, gi... - gi\|187768162\|gb\|EDU32006.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|189363458, gi... - gi\|189363458\|gb\|EDU81877.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|189373159, gi... - gi\|189373159\|gb\|EDU91575.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|168779242, gi... - gi\|189002923\|gb\|EDU71909.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|81240176, gi\|... - gi\|82776028\|ref\|YP_402375.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella dysenteriae Sd197... gi\|217326155, gi... - gi\|217326155\|ref\|ZP_03442239.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia co... EG10079 - 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine repressible / 3-deoxy-D-arabino-... gi\|81244585, gi\|... - gi\|82543174\|ref\|YP_407121.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella boydii Sb227], gi... gi\|209917998, gi... - gi\|209917998\|ref\|YP_002292082.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli SE11]... gi\|192926766, gi... - gi\|75256338\|ref\|ZP_00728008.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|75511356, gi\|... - gi\|75511356\|ref\|ZP_00734041.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|218694171, gi... - gi\|218694171\|ref\|YP_002401838.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli 55989... gi\|170020908, gi... - gi\|170020908\|ref\|YP_001725862.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli ATCC ... gi\|83584861, gi\|... - gi\|83584861\|ref\|ZP_00923520.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|168800814, gi... - gi\|189376981\|gb\|EDU95397.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|195936742 - gi\|195936742\|ref\|ZP_03082124.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli O157:H... gi\|170080414, gi... - gi\|170080414\|ref\|YP_001729734.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine... gi\|194412266, gi... - gi\|75209077\|ref\|ZP_00709335.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|208731490, gi... - gi\|208814842\|ref\|ZP_03256021.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia co... gi\|75228379, gi\|... - gi\|75228379\|ref\|ZP_00715027.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|208808417, gi... - gi\|208808417\|ref\|ZP_03250754.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia co... gi\|187427742, gi... - gi\|75175250\|ref\|ZP_00695560.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|124531871, gi... - gi\|124531871\|ref\|ZP_01701970.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli B], gi... gi\|209400570, gi... - gi\|209400570\|ref\|YP_002269381.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia c... gi\|75194907, gi\|... - gi\|75194907\|ref\|ZP_00704977.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|208737562, gi... - gi\|208822077\|ref\|ZP_03262396.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia co...	488.0	[0..20]	[366..6]
gi\|30749575, gi\|... - gi\|30749576\|pdb\|1N8F\|D Chain D, Crystal Structure Of E24q Mutant Of Phenylalanine-Regulated 3-Deoxy-...	488.0	[0..20]	[366..6]
gi\|62126962, gi\|... - gi\|62179329\|ref\|YP_215746.1\| 3-deoxy-7-phosphoheptulonate synthase [Salmonella enterica subsp. enter...	488.0	[0..20]	[366..49]
gi\|157154975, gi... - gi\|75189768\|ref\|ZP_00703035.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ...	487.0	[0..20]	[366..6]
gi\|30040334, gi\|... - gi\|30062090\|ref\|NP_836261.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella flexneri 2a str. ... gi\|24111977, gi\|... - gi\|24111977\|ref\|NP_706487.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella flexneri 2a str. ... gi\|110614175, gi... - gi\|110804627\|ref\|YP_688147.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella flexneri 5 str. ...	487.0	[0..20]	[366..6]
gi\|27366988, gi\|... - gi\|27366988\|ref\|NP_762515.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Vibrio vulnificus CMCP6], ...	486.0	[0..18]	[367..3]

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Predicted Domain #1

Region A:
Residues: [1-368]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKHTPLLPG DSVFSRCKTE DSRIKGYDPV ISPALIQSEL AASDETLAFV SDQRRQAADI  60
   61 IAGRDDRLLL IVGPCSLHDP VAAKEYAIRL QKEAIKHKKD LHIIMRAYLE KPRTTVGWKG 120
  121 LINDPDLDGS YNINKGIRVA RRIFLELLET GVGIASEMLD TISPQYLADL ICWGAIGART 180
  181 TESQLHRELA SGLSFPIGFK NATDGNIGIA IDAMNSSANP HHFLSVTKQG VVAIVTTTGN 240
  241 PDTHIILRGG KSGTNFDADS VAGAKAKLEE CNKLPSIMID CSHGNSSKNH KNQPKVAACI 300
  301 AEQVANGQKA ITGVMIESHL NEGKQAIPED DLSSMKYGVS VTDACIGWDD TTAVFEQLAA 360
  361 AVRSRRSH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	129.0
Match:	1hfbA
Description:	3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase, AroG)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3-deoxy-7-phosphoheptulonate synthase activity	2.72022882819661	bayes_pls_golite062009
catalytic activity	2.67031204377352	bayes_pls_golite062009
lyase activity	0.740424046054758	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	0.719960432098845	bayes_pls_golite062009
oxo-acid-lyase activity	0.606352769346285	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	0.490222900376021	bayes_pls_golite062009
transferase activity	0.464721888799972	bayes_pls_golite062009
carbon-carbon lyase activity	0.36754360512349	bayes_pls_golite062009
3-deoxy-8-phosphooctulonate synthase activity	0.0356008407895519	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: