YRC Public Data Repository - Protein Structure Prediction

Protein:	med7
Organism:	Schizosaccharomyces pombe
Length:	376 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for med7.

Description	E-value	Query Range	Subject Range
gi\|6474201 - gi\|6474201\|dbj\|BAA87232.1\| Hypothetical nuclear protein [Schizosaccharomyces pombe]	250.0	[0..176]	[374..1]
gi\|55730559 - gi\|55730559\|emb\|CAH92001.1\| hypothetical protein [Pongo abelii] gi\|55730559\|emb\|... - hypothetical protein [Pongo pygmaeus]	178.0	[0..209]	[316..60]
gi\|73954132 - gi\|73954132\|ref\|XP_536456.2\| PREDICTED: similar to Cofactor required for Sp1 transcriptional activat...	173.0	[0..209]	[316..60]
gi\|109487990, gi... - gi\|109490586\|ref\|XP_001069084.1\| PREDICTED: similar to Cofactor required for Sp1 transcriptional act...	172.0	[0..209]	[356..60]
MED7_CANAL - Mediator of RNA polymerase II transcription subunit 7 OS=Candida albicans (strain SC5314 / ATCC MYA-... MED7_CANAL - Mediator of RNA polymerase II transcription subunit 7 OS=Candida albicans GN=MED7 PE=3 SV=1	171.0	[0..224]	[376..164]
MED7_DANRE - Mediator of RNA polymerase II transcription subunit 7 OS=Danio rerio GN=med7 PE=2 SV=1	166.0	[0..209]	[317..60]
gi\|47182712 - gi\|47182712\|emb\|CAG13624.1\| unnamed protein product [Tetraodon nigroviridis]	166.0	[0..209]	[316..24]
MED7_ANOGA - Mediator of RNA polymerase II transcription subunit 7 OS=Anopheles gambiae GN=MED7 PE=3 SV=2 gi\|55241950, gi\|... - gi\|58382667\|ref\|XP_312090.2\| AGAP002823-PA [Anopheles gambiae str. PEST], gi\|55241950\|gb\|EAA07749.3\|...	164.0	[0..209]	[314..62]
MED7_XENTR - Mediator of RNA polymerase II transcription subunit 7 OS=Xenopus tropicalis GN=med7 PE=2 SV=1	162.0	[0..163]	[362..15]

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Predicted Domain #1

Region A:
Residues: [1-106]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPNEGVQLF SAFPPPPPYY KLFTRENIEK VISNMEKEAK HEDDANTLQP KTEEEIESLA  60
   61 KLFKKPSCLT SGTYQMFGDT WRLDEAIPSL KEFGIPELYK DIKDGE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [107-201]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEIEVVEYDP KSNAIVGTSF TRVHDYDKNS PIENEKILED DQHTAMKEKD NESDKTMKDV  60
   61 EEKTEPSLKK EEEDIQMKEP LDSQDTGAVS ASSVN

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.13
Match:	1ykeA
Description:	Structure of the mediator MED7/MED21 subcomplex
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [202-376]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGFRADQKSK DGETSDLIKI PRRAYELRFL SRSLMLNFLE LLGIMAKAPE QFPSKVENIR  60
   61 VLLLNLHHLI NDYRPHQSRE SLIMLLEKQL KHEESQVELL RTHNRQMTET LEKYKSLDFN 120
  121 MEKEGDVIQQ LKSSIKKPLS GAEDEQKSRS MFSKNDEKLK KSLELMEDVI KRDLS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.221849
Match:	1ykeA
Description:	Structure of the mediator MED7/MED21 subcomplex
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits