YRC Public Data Repository - Protein Structure Prediction

Protein:	ptc1
Organism:	Schizosaccharomyces pombe
Length:	347 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ptc1.

Description	E-value	Query Range	Subject Range
gi\|20146110 - gi\|20146110\|dbj\|BAB88944.1\| protein phosphatase 2C [Mesembryanthemum crystallinum]	261.0	[0..40]	[344..2]
P2C10_ORYSJ - Probable protein phosphatase 2C 10 OS=Oryza sativa subsp. japonica GN=Os02g0149800 PE=2 SV=1	254.0	[0..57]	[323..68]
P2C69_ARATH - Probable protein phosphatase 2C 69 OS=Arabidopsis thaliana GN=At5g10740 PE=2 SV=1	251.0	[0..40]	[323..2]
PPM1A_RAT - Protein phosphatase 1A OS=Rattus norvegicus GN=Ppm1a PE=1 SV=1	248.0	[0..58]	[343..8]
PPM1A_RABIT - Protein phosphatase 1A OS=Oryctolagus cuniculus GN=PPM1A PE=2 SV=1	247.0	[0..58]	[343..8]
PPM1A_BOVIN - Protein phosphatase 1A OS=Bos taurus GN=PPM1A PE=2 SV=1	247.0	[0..58]	[343..8]
gi\|114653333 - gi\|114653333\|ref\|XP_001167412.1\| PREDICTED: hypothetical protein LOC452950 isoform 8 [Pan troglodyte...	246.0	[0..58]	[343..56]

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Predicted Domain #1

Region A:
Residues: [1-347]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKGSHPNAGS LLEPLHKLNP FSENSTSGHR KNASDHSADG ETRPIAIEMK DSKGNTVPVG  60
   61 NSRPSKASNW LAGLMEDKNQ RWRRSMEDTH ICLYDFGGNQ DDGFVAVYDG HAGIQASDYC 120
  121 QKNLHKVLLE KVRNEPDRLV TDLMDETFVE VNSKIAKATH NDICGCTAAV AFFRYEKNRT 180
  181 RRVLYTANAG DARIVLCRDG KAIRLSYDHK GSDANESRRV TQLGGLMVQN RINGVLAVTR 240
  241 ALGDTYLKEL VSAHPFTTET RIWNGHDEFF IIACDGLWDV VSDQEAVDFV RNFVSPREAA 300
  301 VRLVEFALKR LSTDNITCIV VNLTRNPGDL DDSGLTADND SYSNDYY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.30103
Match:	1a6qA
Description:	CRYSTAL STRUCTURE OF THE PROTEIN SERINE/THREONINE PHOSPHATASE 2C AT 2 A RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoprotein phosphatase activity	7.29765002420868	bayes_pls_golite062009
phosphatase activity	6.84540130415879	bayes_pls_golite062009
phosphoric ester hydrolase activity	6.63839066304808	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	5.76293366458633	bayes_pls_golite062009
protein serine/threonine phosphatase activity	5.66354576593165	bayes_pls_golite062009
hydrolase activity	4.10826723952347	bayes_pls_golite062009
binding	1.74689317666387	bayes_pls_golite062009
catalytic activity	1.53401212718168	bayes_pls_golite062009
protein binding	0.425331902048676	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: