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View Structure Prediction Details

Protein: pof8
Organism: Schizosaccharomyces pombe
Length: 402 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pof8.

Description E-value Query
Range
Subject
Range
gi|114595731 - gi|114595731|ref|XP_001144487.1| PREDICTED: La ribonucleoprotein domain family, member 7 isoform 11 ...
221.0 [0..220] [401..391]
gi|78070714, gi|... - gi|78070714|gb|AAI07710.1| LARP7 protein [Homo sapiens], gi|119626688|gb|EAX06283.1| HDCMA18P protei...
221.0 [0..220] [401..10]
LARP7_MOUSE - La-related protein 7 OS=Mus musculus GN=Larp7 PE=1 SV=2
gi|151555613, gi... - gi|157170500|gb|AAI53030.1| La ribonucleoprotein domain family, member 7 [synthetic construct], gi|1...
215.0 [0..220] [401..374]

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Predicted Domain #1
Region A:
Residues: [1-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFVPRQLNVR KIKAFTGKEN NSIADGNNNK LKDEHYKHNE ASKEPSHSIS GGLMLNQQDR  60
   61 QLIEPLNPDF LSAVDSILEI YFHRERQKEK VHLAFLIQQD DFWKGIRPNP TQNNLKYALS 120
  121 YVTNALFHFD NSSHMVIRNE NIVLPLDIPL YDRIIYVEPV PATLSNKSLL LAGKLRKYLK 180
  181 EFLPYVDAIG TPEGYAFVIL YKKVDQSALS KLPVPPGWVL LTRKEWTNRE EKYFENQLHL 240
  241 VKASSSDVSN SSNSFPENRY PKLTKVEKQM TKSVSKT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [278-402]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQTDKDEDNL DFTKNLLTRI KNLHPLTNKS TIHSLLSYVF SRQTQNIACE PMYIDYRKDE  60
   61 TEAIIRWKTP LHAETCINAF RTQERKQNSH DDIRAHRKKG SSRPFLIAEL ITGEEEKNYW 120
  121 RMLKK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.32
Match: 1owxA
Description: Lupus LA protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 4.43561246034545 bayes_pls_golite062009
small conjugating protein ligase activity 4.39408082050061 bayes_pls_golite062009
acid-amino acid ligase activity 3.85120824615514 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 3.19116367604486 bayes_pls_golite062009
nucleic acid binding 3.0372165500396 bayes_pls_golite062009
binding 2.88749864706998 bayes_pls_golite062009
RNA binding 2.06552837244801 bayes_pls_golite062009
ligase activity 1.73418602894877 bayes_pls_golite062009
mRNA binding 0.880500251455587 bayes_pls_golite062009
hydrolase activity 0.548889083879905 bayes_pls_golite062009
protein binding 0.361619805766015 bayes_pls_golite062009
DNA binding 0.208935674354032 bayes_pls_golite062009
transcription regulator activity 0.033524725075138 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle