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View Structure Prediction Details

Protein: rpc2
Organism: Schizosaccharomyces pombe
Length: 1165 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rpc2.

Description E-value Query
Range
Subject
Range
gi|108710089 - gi|108710089|gb|ABF97884.1| DNA-directed RNA polymerase II 135 kDa polypeptide, putative, expressed ...
gi|125545063 - gi|125545063|gb|EAY91202.1| hypothetical protein OsI_12811 [Oryza sativa Indica Group]
1296.0 [0..36] [1162..45]
NRPB2_ARATH - DNA-directed RNA polymerase II subunit 2 OS=Arabidopsis thaliana GN=NRPB2 PE=1 SV=2
1284.0 [0..25] [1161..2]
RPB2_SOLLC - DNA-directed RNA polymerase II subunit RPB2 OS=Solanum lycopersicum GN=RPB2 PE=2 SV=1
1280.0 [0..21] [1161..1]
gi|70906409 - gi|70906409|gb|AAZ14928.1| DNA-dependent RNA polymerase II second largest subunit [Coprinellus disse...
1278.0 [0..28] [1159..32]
RPB2_SCHPO - DNA-directed RNA polymerase II subunit RPB2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G...
rpb2 - DNA-directed RNA polymerase II complex subunit Rpb2
1273.0 [0..35] [1161..2]
gi|68300814 - gi|68300814|gb|AAY89348.1| RNA polymerase II second largest subunit [Antirrhinum majus]
1273.0 [0..45] [1161..29]
gi|70794966 - gi|70794966|gb|AAZ08457.1| RNA polymerase II second largest subunit [Rhododendron macrophyllum]
1271.0 [0..45] [1159..20]
gi|218554, gi|479866 - pir||S35548 DNA-directed RNA polymerase (EC 2.7.7.6) II chain 2 - fission yeast (Schizosaccharomyces...
1270.0 [0..35] [1161..2]

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Predicted Domain #1
Region A:
Residues: [1-1165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVNTAGDPQ KSQPKINKGG IGKDESFGAL FKPVYKGKKL ADPVPTIEDK WQLLPAFLKV  60
   61 KGLVKQHLDS YNYFVDVDLK KIVQANEKVT SDVEPWFYLK YLDIRVGAPV RTDADAIQAS 120
  121 ISPHECRLRD LTYGANIYVD IEYTRGKQVV RRRNVPIGRM PVMLRSNKCV LSGKNEMEMA 180
  181 ALNECPLDPG GYFIVKGTEK VILVQEQLSK NRIIVEAEPK KGLWQASVTS STHERKSKTY 240
  241 VITKNGKLYL KHNSVADDIP IVVVLKAMGL QSDQEIFELV AGAEASYQDL FAPSIEECAK 300
  301 LNIYTAQQAL EYIGARVKVN RRAGANRLPP HEEALEVLAA VVLAHINVFN LEFRPKAVYI 360
  361 GIMARRVLMA MVDPLQVDDR DYVGNKRLEL AGQLLALLFE DLFKKFNSDL KLNIDKVLKK 420
  421 PHRTQEFDAY NQLTVHSDHI TQGMVRALST GNWSLKRFKM ERAGVTHVLS RLSYISALGM 480
  481 MTRITSQFEK TRKVSGPRSL QASQFGMLCT SDTPEGEACG LVKNLALMTH ITTDEEEEPI 540
  541 IKLAYAFGIE DIHVISGREL HSHGTYLVYL NGAILGISRY PSLFVASFRK LRRSGKISPF 600
  601 IGIFINTHQR AVFISTDGGR ICRPLIIVQN GLPKVESKHI RLLKEGKWGF EDFLKQGLVE 660
  661 YVDVNEENDS LISVYERDIT PDTTHLEIEP FTILGAVAGL IPYPHHNQSP RNTYQCAMGK 720
  721 QAIGAIAYNQ LQRIDTLLYL MVYPQQPMVK TKTIELIGYD KLPAGQNATV AIMSYSGYDI 780
  781 EDALVLNKSS IDRGFGRCQV FHKHSVIVRK YPNGTHDRIG DPQRDPETGE VVWKHGVVED 840
  841 DGLAGVGCRV QPGQIYVNKQ TPTNALDNSI TLGHTQTVES GYKATPMTYK APEPGYIDKV 900
  901 MLTTTDSDQT LIKVLMRQTR RPELGDKFSS RHGQKGVCGV IVQQEDMPFN DQGICPDIIM 960
  961 NPHGFPSRMT VGKMIELLSG KVGVLRGTLE YGTCFGGTKV EDASRILVEH GYNYSGKDML1020
 1021 TSGITGETLE AYIFMGPIYY QKLKHMVMDK MHARARGPRA VLTRQPTEGR SRDGGLRLGE1080
 1081 MERDCLIAYG ASQLLLERLM ISSDACDVDV CGQCGLLGYK GWCNSCQSTR EVVKMTIPYA1140
 1141 AKLLFQELLS MNIVPRLALE DEFKY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1i3qB
Description: RBP2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA-directed RNA polymerase activity 10.2021663255698 bayes_pls_golite062009
RNA polymerase activity 10.2021663255698 bayes_pls_golite062009
nucleotidyltransferase activity 7.6240729546188 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 6.31198922553685 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 5.44374972993429 bayes_pls_golite062009
transferase activity 4.83218811360621 bayes_pls_golite062009
transcription regulator activity 2.34884279395902 bayes_pls_golite062009
nucleic acid binding 2.33174616086951 bayes_pls_golite062009
DNA binding 2.27079409864244 bayes_pls_golite062009
binding 1.73416306650822 bayes_pls_golite062009
RNA polymerase II transcription mediator activity 1.53259746846673 bayes_pls_golite062009
catalytic activity 1.36406839864424 bayes_pls_golite062009
RNA binding 1.12618950637766 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.847783043631028 bayes_pls_golite062009
protein binding 0.45174975126993 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle