YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC584.15c
Organism:	Schizosaccharomyces pombe
Length:	594 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC584.15c.

Description	E-value	Query Range	Subject Range
gi\|46128141, gi\|... - gi\|46128141\|ref\|XP_388624.1\| hypothetical protein FG08448.1 [Gibberella zeae PH-1], gi\|42548061\|gb\|E...	203.0	[0..9]	[592..12]
gi\|7243133 - gi\|7243133\|dbj\|BAA92614.1\| KIAA1376 protein [Homo sapiens]	200.0	[0..11]	[423..27]
gi\|28972730 - gi\|28972730\|dbj\|BAC65781.1\| mKIAA1376 protein [Mus musculus]	200.0	[0..11]	[423..43]
gi\|57084867 - gi\|57084867\|ref\|XP_546029.1\| PREDICTED: similar to arrestin domain containing 3 isoform 1 [Canis fam...	194.0	[0..11]	[423..4]
ARRD3_BOVIN - Arrestin domain-containing protein 3 OS=Bos taurus GN=ARRDC3 PE=2 SV=1	191.0	[0..11]	[423..4]
gi\|109077981 - gi\|109077981\|ref\|XP_001089534.1\| PREDICTED: similar to arrestin domain containing 3 isoform 3 [Macac...	191.0	[0..11]	[423..4]
gi\|49256119, gi\|... - gi\|49256119\|gb\|AAH72973.1\| MGC82523 protein [Xenopus laevis], gi\|147904392\|ref\|NP_001085581.1\| MGC82...	190.0	[0..10]	[342..11]

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Predicted Domain #1

Region A:
Residues: [1-348]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKIKGGRHK SPVKLFEVRL YNAEANVIVL YGNSMDTSAR LSGIVVLSVS SPIRVKNIKL  60
   61 RLSGRSFVCW ADESRHASPG NRIRRQVVQI LDKSWSFLAP NESAKVIDQG NYEYPFYYEL 120
  121 PPDIPDSIEG IPGCHIIYTL TASLERATQP PTNLETALQF RVIRTIPPNS LDLMHSVSVS 180
  181 DIWPLKVNYE TSIPSKVYAI GSEIPVNITL YPLLKGLDVG KVTLVLKEYC TLFITSKAYS 240
  241 STCRKEFKRA LVKKTIPGLP MVDDYWQDQI MVKIPDSLGE CTQDCDLNCI RVHHKLRLSI 300
  301 SLLNPDGHVS ELRNSLPLSL VISPVMFGAR PTEGVFTGDH NSYVNENI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.0
Match:	1jsyA
Description:	Arrestin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.01555579124143	bayes_pls_golite062009
protein binding	1.50286160643298	bayes_pls_golite062009
ligand-gated ion channel activity	0.0676214219421661	bayes_pls_golite062009
ligand-gated channel activity	0.0676214219421661	bayes_pls_golite062009
cation channel activity	0.0318083563912285	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [349-458]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPSYDKHVFD VLWDGIPSEN PQLQSGFTTP NLSRRNSSDF GPNSPVNIHS NPVPISGQQP  60
   61 SSPASNSNAN FFFGSSPQSM SSEQTDMMSP ITSPLAPFSG VTRRAARTRA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.961
Match:	1pk8A
Description:	Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [459-594]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSASSVFNSQ LQPLQTDLLS PLPSPTSSNS RLPRVRSACT LNVQELSKIP PYYEAHSAFT  60
   61 NVLPLDGLPR YEEATRPSSP TESVEIPSNT TTIAPSPVPT IIAPALPSTP APPLPSHPMA 120
  121 TRKSLSSTNL VRRGVR

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: