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View Structure Prediction Details

Protein: ppk38
Organism: Schizosaccharomyces pombe
Length: 650 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ppk38.

Description E-value Query
Range
Subject
Range
gi|114654987 - gi|114654987|ref|XP_001138333.1| PREDICTED: MAP/microtubule affinity-regulating kinase 3 isoform 12 ...
330.0 [0..4] [635..29]
gi|73964123 - gi|73964123|ref|XP_868656.1| PREDICTED: similar to MAP/microtubule affinity-regulating kinase 3 isof...
329.0 [0..4] [635..29]
gi|46852166 - gi|46852166|ref|NP_002367.4| MAP/microtubule affinity-regulating kinase 3 isoform c [Homo sapiens]
326.0 [0..4] [635..29]
gi|61354596 - gi|61354596|gb|AAX41026.1| MAP/microtubule affinity-regulating kinase 3 [synthetic construct]
326.0 [0..4] [635..29]

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Predicted Domain #1
Region A:
Residues: [1-317]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNETNNTSLL PVSSLPSGLL PVGFSCTVEK FSVTVKRYLA EGGFSHVYLV QLVFPGKPPF  60
   61 EAVLKRIFAT DAMALRAVHE EVRTMKLVSN QKRCVSYYGS EFFRTSKNQF EVLVLLEYCP 120
  121 CGGLIDFLNT RLQVRLSEQE ILKIASDVTE AVAVMHYLKP PLIHRDLKIE NVLLAAPNSY 180
  181 KLCDFGSACH PIPGAKTAAE AKQLEYDIEK FTTWQYRCPE MINVHKGFGI DEKSDIWALG 240
  241 VLFYKLCYYT TPFEHQGLAA IMNVSYAFPT FPPYSDRLKR LISTLLQQYP WQRPNIYQTF 300
  301 CEICKMRNVP IHIYDIY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.0
Match: 1mq4A
Description: Crystal Structure of Aurora-A Protein Kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [318-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGKNVSSCNP SGSEYLQHAS KLENSGIHQS KSSVFPQPAS AMKPMASPML PNVNSMPYLS  60
   61 NGDHNNNGNT SSPVSRFSYG QHTSNVP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [405-546]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STQKLPSNFR VTQGAPPSHT YGPPPPVQPK PKISPTTPRL STLALADDMF SSTAKETVPT  60
   61 NEAVFTGDVK SFDSQESNII ESEPLSASNA SGKPRTSVNR LVDRYNHTSS LNKVAAAPAP 120
  121 VPKPVNLKSV ENPQNNISAP TP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [547-650]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSLQSSNAPV GLGEVESKSV PPTNMATERG VVGRRASMSI AVNARRVSKP EKEHTNPNAE  60
   61 QGDVIPEKPM SIKERMNMLM TKTDYEKPKV EGYGRYTDVQ QTKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle