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View Structure Prediction Details

Protein: mfh2
Organism: Schizosaccharomyces pombe
Length: 783 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mfh2.

Description E-value Query
Range
Subject
Range
gi|38201710, gi|... - gi|38201710|ref|NP_006377.2| DEAD box polypeptide 17 isoform 1 [Homo sapiens], gi|110611789|gb|AAH00...
283.0 [0..17] [470..105]
gi|109482569 - gi|109482569|ref|XP_001076554.1| PREDICTED: similar to DEAD box polypeptide 17 isoform p82 [Rattus n...
283.0 [0..17] [470..191]
gi|109094275 - gi|109094275|ref|XP_001092491.1| PREDICTED: similar to DEAD box polypeptide 17 isoform p82 [Macaca m...
283.0 [0..17] [470..216]
gi|114686445 - gi|114686445|ref|XP_525595.2| PREDICTED: DEAD box polypeptide 17 [Pan troglodytes]
283.0 [0..17] [458..203]
RH30_ARATH - DEAD-box ATP-dependent RNA helicase 30 OS=Arabidopsis thaliana GN=RH30 PE=2 SV=2
278.0 [0..42] [449..125]
gi|74210167 - gi|74210167|dbj|BAE21355.1| unnamed protein product [Mus musculus]
278.0 [0..26] [513..118]

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Predicted Domain #1
Region A:
Residues: [1-91]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIVLRDSSDY SDSEVDLPSI EVNGERGNVP TSVLCNVEGS LLNSNPALRQ PNLKCIKHNQ  60
   61 DVENTTFQLD LRGCRVPSSQ PQVITELENN I

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [92-682]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DIPKNIDAMQ NWIFPQTQQY RNYQKEFCEQ ALFHNLLLAL PTGLGKTFIA AVVMLNYFRW  60
   61 FPESKIIFLA PTKPLLLQQR VACSNVAGMS PGATAELNGE VSPDRRLFEY NTKRVFFMTP 120
  121 QTLQNDLKEH LLDAKSIICL IFDEAHRATG NHSYAQVMRA VLRSNSHFRV LGLTATPGSS 180
  181 TASVQKVVDC LHISKLIVRN EESIDIRSYV FHKKIQLIKV TISSEMNILK SDFANLYRPY 240
  241 FNFLRQKKLI PINCECLNIK AYTLFVSLRK YSFSSKNVQS KEKSKIMSCF TLLISCAHIT 300
  301 YLLDCHGIIQ FYQKLVETKN KAEGKGSGQS FWLFTSKPFA FYLEHLHNKI QGLSLNHPKM 360
  361 NHLLELLKEH FKDTSEGYQN QRVMIFTEFR NTAEYITTTL LAIRPMVRAS LFIGQANSAY 420
  421 STGMNQMQQK ETIDQFRAGV INTLVATSIG EEGLDIGDTD MIICYDASSS PIRTIQRMGR 480
  481 TGRKKSGKVF VLLTEDCEDS KWERSQVSYR RVQKVIESGK KIALKKDVPR LIPSNIQPIF 540
  541 KFQALQNNAD ATLILNSYNN NSSSLSPVNT LANQAHSRSK RYLPFIVDDV F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.0
Match: 1wp9A
Description: Crystal structure of Pyrococcus furiosus Hef helicase domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [683-783]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDMESNLRVP TEDAKIKRFK SDYRSCIYNA RRNVFSKPTY MGDKLTKFAK VPHSLLTLSI  60
   61 YRRGRLLQQC SPSSVTKYLK YEEKFKRKRM KKTSNALFQS T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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