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View Structure Prediction Details

Protein: SPBC27B12.11c
Organism: Schizosaccharomyces pombe
Length: 738 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC27B12.11c.

Description E-value Query
Range
Subject
Range
TCNA_TRYCR - Sialidase OS=Trypanosoma cruzi GN=TCNA PE=2 SV=1
210.0 [0..10] [547..578]
gi|70869911 - gi|70869911|gb|EAN84377.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71407532 - gi|71407532|ref|XP_806228.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
192.0 [0..43] [544..664]
gi|39579415, gi|... - gi|39579415|emb|CAE56721.1| Hypothetical protein CBG24508 [Caenorhabditis briggsae], gi|187040086|em...
188.0 [0..4] [545..6]
gi|31540577 - gi|31540577|gb|AAP48996.1| cellulosomal scaffoldin anchoring protein C; ScaC [Acetivibrio cellulolyt...
182.0 [0..4] [487..464]
SLP1_CLOTM, SLAP... - (Q06852) Cell surface glycoprotein 1 precursor (Outer layer protein B) (S-layer protein 1), Cell sur...
180.0 [0..4] [551..771]
gi|33310026 - gi|33310026|gb|AAQ03243.1|AF414112_1 putative cell wall protein FLO11p [Candida albicans]
gi|68482880, gi|... - gi|68482880|ref|XP_714666.1| putative cell wall adhesin [Candida albicans SC5314], gi|46436253|gb|EA...
176.0 [0..8] [553..145]
SLAP1_CLOTH - Cell surface glycoprotein 1 OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 ...
175.0 [0..4] [549..1377]
gi|45190584, gi|... - gi|45190584|ref|NP_984838.1| AEL023Cp [Ashbya gossypii ATCC 10895], gi|44983526|gb|AAS52662.1| AEL02...
gi|44983526 - gi|44983526|gb|AAS52662.1| AEL023Cp [Ashbya gossypii ATCC 10895]
168.0 [0..9] [552..324]
gi|15828996 - gi|15828996|ref|NP_326356.1| lipoprotein VSAC (fragment) [Mycoplasma pulmonis UAB CTIP]
gi|14089939, gi|... - pir||E90577 lipoprotein vsaC [imported] - Mycoplasma pulmonis (strain UAB CTIP) (fragment), gi|14089...
167.0 [0..4] [552..115]

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Predicted Domain #1
Region A:
Residues: [1-72]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKKVVQSAS KNEELDPHYK RSSVPFPYGL PDYDAEYQFI NHHMQQLLTR PVEGTHSASV  60
   61 HPSTSSTSHI SS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [73-248]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSAFSVQNPN PNDAPFVGNI GLDASGFSSG GMSEYYPRSV SMQQSQDVHF QNTEIPYYHR  60
   61 SPSSDSFSPG VVASVNPNSN NSPTFYSNPP ALSNIPIPLN NSPYRPEDAY FQLQGAGVKA 120
  121 DINPYNLSPY SQYGPEGTAY SNAQAHHQDG APLQRVCSAP DPPKTSMPPF GSAGSP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [249-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPNRSLNVSN NTTPPLSTVN KIIKKPKATT GKVKKRLPQA KRACAKCQKD NKKCDDARPC  60
   61 QRCIKAKTDC IDLPRKKRPT GVRRGPYKKL SDTSNNTKST TASSGHSTQD SLSSKMLDPS 120
  121 SDNQFAMSSR QMDENGMAQY PSSA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.38
Match: 1pyiA
Description: PPR1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.34861813464065 bayes_pls_golite062009
DNA binding 4.03985756894684 bayes_pls_golite062009
nucleic acid binding 3.97978190843512 bayes_pls_golite062009
transcription factor activity 2.87348461329489 bayes_pls_golite062009
binding 2.82809978070212 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.80191339934741 bayes_pls_golite062009
sequence-specific DNA binding 1.67344049333457 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.50774349911815 bayes_pls_golite062009
transcription activator activity 0.822069987038721 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [393-551]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKQELNLQPQ ILVSSASKNF QPNVTPPFAV HHDHFNSTSM DGVAVSNMDE TGTSSAGSKP  60
   61 FNRKSRNRSF TNPVGMTEEH FLREYAQHSV ANPSLLIHQI HGLPSEQVHG LLSHTELGNA 120
  121 MHNQPTYNES SIAAENVNNW MLETNDHENL SMQSHFEVP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [552-738]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLKMNHHDSS FFDRHIDQTA MPGQNQHGTV KNMETMHHFY PDVHNSEFPA APNPVKSQVP  60
   61 YYYQSQAADD EEEDVPDHQP SWRGRIHSFS IATDSSQHVV ERPCIHSLRG IHGQQDGGLE 120
  121 QHDGDHVNML PDTHAEELAY TSMLLFHDIP TRDIRPDFNV HELVDHGTYP NFHQNQADSF 180
  181 KNHPFRQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle