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View Structure Prediction Details

Protein: SPBC28F2.11
Organism: Schizosaccharomyces pombe
Length: 310 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC28F2.11.

Description E-value Query
Range		 Subject
Range
gi|109511369, gi... - gi|109514150|ref|XP_001067329.1| PREDICTED: similar to High mobility group protein 4 (HMG-4) (High m...
 154.0 [0..15] [205..360]
gi|76609479 - gi|76609479|ref|XP_610926.2| PREDICTED: similar to high-mobility group box 3 [Bos taurus]
 152.0 [0..7] [214..341]
gi|91080287 - gi|91080287|ref|XP_973934.1| PREDICTED: similar to High mobility group protein DSP1 (Dorsal switch p...
 147.0 [0..16] [190..684]
gi|38049113 - gi|38049113|gb|AAR10364.1| sex determining region Y protein [Odobenus rosmarus]
 141.0 [0..99] [287..34]
SRY_HALGR - Sex-determining region Y protein OS=Halichoerus grypus GN=SRY PE=3 SV=2
 140.0 [0..96] [291..31]
SRY_PHOLR - Sex-determining region Y protein OS=Phoca largha GN=SRY PE=3 SV=1
SRY_PHOVI - Sex-determining region Y protein OS=Phoca vitulina GN=SRY PE=3 SV=1
 140.0 [0..96] [291..31]
SRY_PUSHI - Sex-determining region Y protein OS=Pusa hispida GN=SRY PE=3 SV=1
 140.0 [0..96] [291..31]
gi|85719141 - gi|85719141|dbj|BAE78533.1| sex determining region Y [Rangifer tarandus]
 139.0 [0..79] [291..14]
SRY_HYDLE - Sex-determining region Y protein OS=Hydrurga leptonyx GN=SRY PE=3 SV=1
 139.0 [0..96] [287..31]

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Predicted Domain #1
Region A:
Residues: [1-109] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQNSTQLEK ISGSFTRLAE AFQLALTACR EIEESLPSIL GEKSEVSKPF KPAVTDPSNA  60
   61 KKEINMAIES PSKKATSPKK ATPAAVAPVE ATSAVDTSEA VASMTPNKR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [110-310] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KARDPAQPKR PPSAYNLFQK NQRSEIKESL GEKSNDVKEV NKAMHEKWGS LSEDDRKTYE  60
   61 EEASKLREAY EEEMAAYNAS KENASVADSR VTAEETSTKP SEDLSSPTKK DLIDFSETRP 120
  121 LAQASRATPD IKEQHAKKPK RKHTRSTVPT SNVEPVSQPQ PSPDKIVSSP NPPSAKREKK 180
  181 KRRKSSMSSS ITTPPTAKVA N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.69897
Match: 2gzkA
Description: No description for 2gzkA was found.

Predicted functions:

Term Confidence Notes
binding 3.1918149935012 bayes_pls_golite062009
DNA binding 2.9192628885142 bayes_pls_golite062009
nucleic acid binding 2.69023297073035 bayes_pls_golite062009
transcription regulator activity 2.58116094906635 bayes_pls_golite062009
transcription factor activity 1.78719688305492 bayes_pls_golite062009
sequence-specific DNA binding 1.45429159567789 bayes_pls_golite062009
transcription repressor activity 1.20795951017807 bayes_pls_golite062009
protein binding 1.131658134984 bayes_pls_golite062009
transcription factor binding 0.3855089242113 bayes_pls_golite062009
chromatin binding 0.26686706452968 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.1389551657237 bayes_pls_golite062009
transcription activator activity 0.0268189092037101 bayes_pls_golite062009
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