YRC Public Data Repository - Protein Structure Prediction

Protein:	liz1
Organism:	Schizosaccharomyces pombe
Length:	514 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for liz1.

Description	E-value	Query Range	Subject Range
gi\|67668083, gi\|... - gi\|67668083\|ref\|ZP_00465278.1\| General substrate transporter:Major facilitator superfamily [Burkhold...	235.0	[0..6]	[457..1019]
gi\|49527412 - gi\|49527412\|emb\|CAG61052.1\| unnamed protein product [Candida glabrata] gi\|50291337, gi\|... - gi\|50291337\|ref\|XP_448101.1\| unnamed protein product [Candida glabrata], gi\|49527412\|emb\|CAG61052.1\|...	223.0	[0..3]	[511..93]
gi\|67903516, gi\|... - gi\|67903516\|ref\|XP_682014.1\| hypothetical protein AN8745.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	216.0	[0..2]	[496..13]
gi\|90307566, gi\|... - gi\|90307566\|gb\|EAS37197.1\| hypothetical protein CIMG_02551 [Coccidioides immitis RS], gi\|119196353\|r...	209.0	[0..5]	[461..227]
gi\|68465998, gi\|... - gi\|68465998\|ref\|XP_723067.1\| sugar transporter-like protein [Candida albicans SC5314], gi\|68465705\|r... orf19.6005, orf1... - HGT5 CGDID:CAL0005021 Assembly 19, Contig19-10236 (305167, 302933) CDS, reverse complemented, transl...	209.0	[0..26]	[494..188]
gi\|169764102 - gi\|169764102\|ref\|XP_001727951.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83770979 - gi\|83770979\|dbj\|BAE61112.1\| unnamed protein product [Aspergillus oryzae]	206.0	[0..12]	[507..193]
SNF3 - Plasma membrane low glucose sensor that regulates glucose transport; contains 12 predicted transmemb... SNF3_YEAST - High-affinity glucose transporter SNF3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=S...	204.0	[0..4]	[476..72]
gi\|115402325, gi... - gi\|115402325\|ref\|XP_001217239.1\| hypothetical protein ATEG_08653 [Aspergillus terreus NIH2624], gi\|1...	200.0	[0..13]	[506..33]
gi\|85080149 - gi\|85080149\|ref\|XP_956491.1\| hypothetical protein [Neurospora crassa OR74A] gi\|32415545, gi\|... - gi\|32415545\|ref\|XP_328252.1\| hypothetical protein [Neurospora crassa], gi\|28917557\|gb\|EAA27255.1\| hy...	198.0	[0..14]	[461..226]
gi\|50302413, gi\|... - gi\|50302413\|ref\|XP_451141.1\| unnamed protein product [Kluyveromyces lactis], gi\|49640272\|emb\|CAH0272... gi\|49640272 - gi\|49640272\|emb\|CAH02729.1\| KLLA0A03223p [Kluyveromyces lactis]	197.0	[0..26]	[465..113]

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Predicted Domain #1

Region A:
Residues: [1-514]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALLNRLAKT FSPYYGLNKV EQKLLIKIDW FILSYCCVSY FINYLDRSSI NNAYLSGMQE  60
   61 DLKMHGNELQ DINVVFTCGY IIGQLPGSYA LQRVPARLWF SVMNILWGLM TIFSFAVHSV 120
  121 RALMILRFFM AVAEASTFAG THYILGAWYK ESELCKRAGI FSASGLVGTM FAGYLQTAVH 180
  181 SSLNGKGGLS GWRWLFIIDG ILTIPLSLYG LFLFPDVPET TKAPYFTEQE KELSFKRLPA 240
  241 RPKKKPLTLK AIKDIVRSWR IYGLCILWIF SGETQAIAVN VLMGQWMKWS NKFSVAQINN 300
  301 YPTVITAVGV VSTLGASVIS DKLAGNPRWP FGLFLCVITT VSATILLAWN VPDGAKFFAY 360
  361 FASGCTYAGQ AVWFSWANDI CRDNDQERGV VVFLMNMCQN IWHIWWAPIM YPNTDTPRFI 420
  421 KGLIGLLVVG GIVFVSSCIV SYMQIRDKRI KRSIQDAKDF DDVFTEHESL ELKKIGKNDE 480
  481 ESLNTTNAVK EISSPGLVIT RQRISMPKET NAQD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.69897
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
substrate-specific transmembrane transporter activity	5.46247398538901	bayes_pls_golite062009
ion transmembrane transporter activity	4.58978526526921	bayes_pls_golite062009
transporter activity	4.09176719149278	bayes_pls_golite062009
anion transmembrane transporter activity	3.94605227012838	bayes_pls_golite062009
cation transmembrane transporter activity	3.88180006470231	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	2.52916479889426	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
binding	1.3181781780038	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
phosphate transmembrane transporter activity	0.312628600969375	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: