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View Structure Prediction Details

Protein: dsl-5
Organism: Caenorhabditis elegans
Length: 302 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dsl-5.

Description E-value Query
Range
Subject
Range
gi|115893463, gi... - gi|115930648|ref|XP_001178590.1| PREDICTED: similar to fibropellin Ib [Strongylocentrotus purpuratus...
283.0 [0..11] [300..1532]

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Predicted Domain #1
Region A:
Residues: [1-224]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLLAISFLF ITFIIESIIC SGYLELHIQS PHIQTAIVNI SSNFRTEKSK IVHLKLKSNV  60
   61 PFNVTRIPVN FDNIYNITIK CGKSEEDGKF NSYFKNSTPK YLGLTDTTIV STVHPRVGLL 120
  121 SPAAVARPLN GIRIVIGCNK NWFGEKCETF CDENKATNSG KHCNFQGKPS CLNGLTGSKC 180
  181 EKLIVPKLCN CENGGVCIDS NPKPICECSK AYRGEKCEKK HISA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 1n7dA
Description: Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.44119144078508 bayes_pls_golite062009
receptor binding 1.40618339011373 bayes_pls_golite062009
protein binding 1.15716342217655 bayes_pls_golite062009
growth factor activity 0.25853515067422 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [225-302]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLSSHYKGDF WNFRMTFWQL IFSNLVENEL AEISKSEAWE TINNLLGNVS DTPFANRPNN  60
   61 TETFPITGSV NLDNVDII

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle