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View Structure Prediction Details

Protein: asp-5
Organism: Caenorhabditis elegans
Length: 393 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for asp-5.

Description E-value Query
Range
Subject
Range
gi|118344558, gi... - gi|55771082|dbj|BAD69801.1| cathepsin D1 [Takifugu rubripes], gi|118344558|ref|NP_001072052.1| cathe...
353.0 [0..1] [390..1]

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Predicted Domain #1
Region A:
Residues: [1-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTTFVALVA LLGLCSATVV QHKLIYRESI KMQMMRRGEW GAYVQHKAAL RDADPAVYAN  60
   61 APQNVNDFGD FEYLGNITIG TPPQPFLVVL DTGSSNLWVP GPSCDGSCKG KREYQSTKSS 120
  121 TFKANGKPWQ IQYGSGNAKG YLGEDTVAFG AVTEKQLPVP STTFGIATHI SSDFKNDAAE 180
  181 GILGLAFTSL AVDHVVPPLI NAINQGLLDQ PLFTVWLEHK GSANDVGGGV FTYGAVDTTN 240
  241 CGPVIAYQPL SSATYYQFVA DSFKLGSYSN SKKYQVISDT GTSFLGGPKA VVAGLASALG 300
  301 ATYHSNDDSY YVPCATNIGT LDITIGGKVY SINPVNYIVD VGMGDTCVFA AFAFNNFGFG 360
  361 PAWILGDPFI RQFCNIYDIG GQRMGFANSL QAN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 86.0
Match: 2psgA
Description: REFINED STRUCTURE OF PORCINE PEPSINOGEN AT 1.8 ANGSTROMS RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
aspartic-type endopeptidase activity 7.9145950161796 bayes_pls_golite062009
aspartic-type peptidase activity 7.9145950161796 bayes_pls_golite062009
peptidase activity 5.78181196721293 bayes_pls_golite062009
endopeptidase activity 5.4888481808613 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 5.39972232367526 bayes_pls_golite062009
hydrolase activity 4.34796304893506 bayes_pls_golite062009
catalytic activity 1.54514410489082 bayes_pls_golite062009
binding 1.10054369202721 bayes_pls_golite062009
receptor binding 0.561225023505917 bayes_pls_golite062009
protein binding 0.193907750061394 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle