| Protein: | nhr-31 |
| Organism: | Caenorhabditis elegans |
| Length: | 583 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-31.
| Description | E-value | Query Range |
Subject Range |
|
|
420.0 | [0..1] | [583..13] |
|
Region A: Residues: [1-183] |
1 11 21 31 41 51
| | | | | |
1 MEQLDVEDWE YWGDEYLEEE PTYAIRPGTR VVKVERVPMM RGDLRTSGAT SSSGPATSYI 60
61 IRPSDKQPTV SSGGSQNGDS VCAVCGDGIA KLHYGVLACY GCKGFFRRTL TGKYRYACRF 120
121 SNNCIVDKFQ RNSCRYCRFQ RCIQAGMDPK AVRPDRDQTG KQKVPRIKKK QIDEELLNHM 180
181 MRL
|
| Detection Method: |  |
| Confidence: | 29.0 |
| Match: | 2a66A |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [184-468] |
1 11 21 31 41 51
| | | | | |
1 QGDDWSRKLP VETRILLMQL MSIEDKVVKG DNNMSAQNTA KDPKSISLRE MFESKPALDG 60
61 RRMEIGYEPF RMARTEELGV IAHRRAIAAV DWVDSLTEIA DAVDTEDKVA LVKSCYSPLT 120
121 IFNFSARTAQ NTKNPDILCL CSHSFVPRRL PPEFNETNHL SNFLIDRTLN ELVAPLRKLN 180
181 LKEEEIVPLK AIIILNPNAK GLSEHARHAI SELRDKVQDM LFQIVKELHP IYSASSRFGN 240
241 LLLLLPTITT LSGLMSENMH FCQALGGRAS GDNLLAEMFG DRTFD
|
| Detection Method: | |
| Confidence: | 46.30103 |
| Match: | 1lbdA |
| Description: | LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription activator binding | 2.98235973123409 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| receptor activity | 2.62895787183554 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| transcription coactivator activity | 2.27959329058894 | bayes_pls_golite062009 |
| molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| ecdysteroid hormone receptor activity | 1.71585537346083 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.60419100774741 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| promoter binding | 1.28787959668198 | bayes_pls_golite062009 |
| palmitoyl-CoA hydrolase activity | 1.23181585568439 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| hormone receptor binding | 0.95284349923679 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.47826452126899 | bayes_pls_golite062009 |
| lipid binding | 0.475303782949439 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.42652610679613 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
|
Region A: Residues: [469-583] |
1 11 21 31 41 51
| | | | | |
1 DQLISSSISP PLFENPAEIC LESISPPMSD RRFVRRVDVA TQTNDDLLSS GPYLPHSNSC 60
61 SSMLNAGYSP PMLSTSPFPL LDDNDSAFQN DISLTELNGC EEFFSQLMDQ PIIDS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
