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View Structure Prediction Details

Protein: mua-6
Organism: Caenorhabditis elegans
Length: 581 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mua-6.

Description E-value Query
Range
Subject
Range
gi|114560153 - gi|114560153|ref|XP_513875.2| PREDICTED: lamin A/C [Pan troglodytes]
314.0 [0..3] [577..388]

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Predicted Domain #1
Region A:
Residues: [1-70]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDPDSYRSS ITSRPSFNRT VTSSSQNYGA PGSGNRVLKI VTETHSSSVS SGLSPYGQNA  60
   61 ASTIRDNRER 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [71-424]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKKEIMELND RLASYIEKVR FLDAQNRKLD ADLKMLQGRF GKSTGSVKVM YEMEITTATN  60
   61 VVKQTGKDHG ETEKEIRKLQ DQLDELRKKF EEAQRGRAED RLKIDDLLVT LSNLEAEINL 120
  121 LKRRIALLEE EVARLKKENF RLTSELQRVR IELDQETLLR IDNQNKVKTI LEEIDFMKRG 180
  181 FETELKELQA QAARDTTSEN REYFKNELAN AMRDIRAEYD QIMNGNRNDM ESWYQLRVQE 240
  241 INTQSNRQNA ENNYQKEEVK RLRNQTSELR QKLSDLESRN LLLEKQIEDL NYQLEDDQRS 300
  301 YEAALNDKDA QIRKLREECQ ALMVELQMLL DTKQTLDGEL KVYRQMLEGN SEGN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.39794
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [425-504]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLRQLVEKVV RTSAINEEAD TETMRVVKGE HSSRTSYQRS AKGNVAIKET SPEGKFVILE  60
   61 NTHRAKEEPL GDWKLKRKID 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.154902
Match: 2dfsA
Description: No description for 2dfsA was found.

Predicted Domain #4
Region A:
Residues: [505-581]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKREIVFTFP SDYILHPFQS VKIFARGQGI ANPPEVLIFE GDETFGVGAN VQTILYNNKG  60
   61 EERATHIQRQ SQQTTSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.0
Match: 1ivtA
Description: Lamin A/C globular tail domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural molecule activity 2.40638781086824 bayes_pls_golite062009
binding 2.29024114419453 bayes_pls_golite062009
protein binding 2.1850626714936 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle