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View Structure Prediction Details

Protein: ifta-2
Organism: Caenorhabditis elegans
Length: 252 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ifta-2.

Description E-value Query
Range		 Subject
Range
gi|50738954 - gi|50738954|ref|XP_419342.1| PREDICTED: similar to ras-related protein [Gallus gallus]
 166.0 [0..26] [241..197]
gi|37360618 - gi|37360618|dbj|BAC98287.1| mKIAA3012 protein [Mus musculus]
 165.0 [0..17] [241..48]
gi|103720 - gi|103720|pir||D38625 GTP-binding protein o-rab1 - electric ray (Discopyge ommata)
 164.0 [0..21] [241..1]
rab-1 - RAS-related protein status:Confirmed UniProt:Q9UAQ6 protein_id:AAC69218.1
 164.0 [0..18] [235..1]
CRE16067, FL81_1... - RP15185 WBGene00061078 locus:Cre-rab-1 status:Confirmed, null
gi|157761211 - gi|157761211|ref|XP_001672948.1| Hypothetical protein CBG01077 [Caenorhabditis briggsae AF16]
gi|39588485, gi|... - gi|39588485|emb|CAE58008.1| Hypothetical protein CBG01077 [Caenorhabditis briggsae], gi|187038224|em...
 164.0 [0..18] [235..1]
gi|148230336, gi... - gi|27924279|gb|AAH45014.1| Rab1-prov protein [Xenopus laevis], gi|148230336|ref|NP_001080138.1| RAB1...
gi|52345478, gi|... - gi|52345478|ref|NP_001004787.1| RAB1A, member RAS oncogene family [Xenopus (Silurana) tropicalis], g...
 162.0 [0..18] [241..1]
RAB1A_PIG - Ras-related protein Rab-1A OS=Sus scrofa GN=RAB1A PE=2 SV=3
 162.0 [0..18] [241..1]
gi|61365844, gi|... - gi|61365844|gb|AAX42772.1| RAB1A member RAS oncogene family [synthetic construct], gi|54695924|gb|AA...
 162.0 [0..18] [241..1]
gi|53733986 - gb|AAH83951.1| Unknown (protein for MGC:97957) [Xenopus laevis]
gi|55741705 - ref|NP_001003153.1| RAB1A, member RAS oncogene family [Canis familiaris]
gi|120419448, gi... - gi|76629653|ref|XP_869337.1| PREDICTED: similar to RAB1, member RAS oncogene family isoform 2 [Bos t...
gi|109103156 - gi|109103156|ref|XP_001090072.1| PREDICTED: similar to RAB1, member RAS oncogene family isoform 4 [M...
gi|61355917, gi|... - gi|61355926|gb|AAX41191.1| RAB1A member RAS oncogene family [synthetic construct], gi|61355917|gb|AA...
tr|G1TCS8|G1TCS8... - pep:novel chromosome:oryCun2:2:121177308:121212010:1 gene:ENSOCUG00000017003 transcript:ENSOCUT00000...
RAB1A - RAB1A, member RAS oncogene family
RAB1A_RAT - Ras-related protein Rab-1A OS=Rattus norvegicus GN=Rab1A PE=1 SV=3
RAB1A_CANLF - Ras-related protein Rab-1A OS=Canis lupus familiaris GN=RAB1A PE=1 SV=3
gi|159906367 - gi|159906367|gb|ABX10872.1| RAB1A [Capra hircus]
RAB1A_MOUSE - Ras-related protein Rab-1A OS=Mus musculus GN=Rab1A PE=1 SV=3
tr|M3VYP9|M3VYP9... - RAB1A, member RAS oncogene family OS=Felis catus GN=RAB1A PE=4 SV=1
gi|149727528 - gi|149727528|ref|XP_001493347.1| PREDICTED: similar to RAB1A, member RAS oncogene family [Equus caba...
 161.0 [0..18] [241..1]
gi|2144601, gi|2... - pir||TVRTYP GTP-binding protein Rab1 - rat, gi|206553|gb|AAA42006.1| ras protein
 161.0 [0..18] [241..1]

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Predicted Domain #1
Region A:
Residues: [1-252] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATENPQTWA LWLILSEMAS DMQEDKKVAK ILVLGPPKAG KTTLCTFLAD FMEDGDTLKK  60
   61 GEDSGERERK FEFEFTSVYR PTKGVRIQEF ETHEFFTEQE QNELGGTRRL EDSEIQLWDV 120
  121 SGDKKYEDCW PAIKENAEGV ILVVNPEEHK GSDLQQWFYE FVEKENIDLS CVMVILNEQG 180
  181 AKKTNHEQIS GFEILPKLRG VHHVAHHFGS EAMQVKMEVN SFMASVLKMD QRQMGSGVDH 240
  241 GLGYADEQED DF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.522879
Match: 2folA
Description: Crystal structure of human RAB1A in complex with GDP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleoside-triphosphatase activity 1.77465535798537 bayes_pls_golite062009
binding 1.7440092435568 bayes_pls_golite062009
pyrophosphatase activity 1.72771981973648 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.70775631232424 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.70592257989501 bayes_pls_golite062009
transporter activity 1.17593506797758 bayes_pls_golite062009
ATPase activity 1.16412666242905 bayes_pls_golite062009
ATPase activity, coupled 1.01662962037416 bayes_pls_golite062009
transmembrane transporter activity 1.01556109575824 bayes_pls_golite062009
hydrolase activity 0.812500703771977 bayes_pls_golite062009
active transmembrane transporter activity 0.718484047943123 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.644921163406031 bayes_pls_golite062009
primary active transmembrane transporter activity 0.642988046660653 bayes_pls_golite062009
purine nucleotide binding 0.632697310016186 bayes_pls_golite062009
purine ribonucleotide binding 0.626266240374543 bayes_pls_golite062009
ribonucleotide binding 0.626051755806866 bayes_pls_golite062009
nucleotide binding 0.621689558153948 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.614658238315815 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.613207201020795 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.611580817005953 bayes_pls_golite062009
GTPase activity 0.112920351857443 bayes_pls_golite062009
ATP binding 0.0857213487022991 bayes_pls_golite062009
adenyl ribonucleotide binding 0.0562710379889879 bayes_pls_golite062009
adenyl nucleotide binding 0.0492207907687829 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle