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View Structure Prediction Details

Protein: clec-73
Organism: Caenorhabditis elegans
Length: 577 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for clec-73.

Description E-value Query
Range
Subject
Range
clec-79 - clec family, C-type lectin status:Partially_confirmed UniProt:Q20528 protein_id:AAC24390.1
335.0 [0..1] [577..1]

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Predicted Domain #1
Region A:
Residues: [1-91]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTKVVSVWL GFIVSAFFTT SWGLLLNSDE GFEKACKQSG GDYTQRAGND SNTGDICLMT  60
   61 FQAVATDMDA ARDFCNIKAP WRLREAKIDK S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [92-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDSIPVIICD VEATFTCNAG WIQMFGYCFK MSEVHDRYTR EKAEQYCKDQ AGPSFQGEIA  60
   61 GIHHRYILTP WRSYFTRLQQ FWIRAPETWD EYVIKTDKVD GDNLALSFYD VHPDFSVPQN 120
  121 AMIKINGKVE LQALCQYKPA ITPAEINYMG RRYSEIYYPT VPVKDGIIVR SASSYTRSSN 180
  181 QSDVCKKVL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.39794
Match: 1tdqB
Description: Structural basis for the interactions between tenascins and the C-type lectin domains from lecticans: evidence for a cross-linking role for tenascins
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.13629480035749 bayes_pls_golite062009
carbohydrate binding 0.44675717945952 bayes_pls_golite062009
protein binding 0.059857076934361 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [281-400]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPYMYSKESQ FFPDPDSMEQ LAKLEPEAYS LMRSPLVSNS VERYRTNRYC QAPSNPHYEV  60
   61 VLGGKKTANF VVEENKIKGK PTCDNMMSVS ISHFKGQAPE FHPMVDSQSL PIWCKLGKVV 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [401-577]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYKYKVTPGW TDFRRLNGQV ALHWLSKDKL TFADAAAACE AKGANLAGIN SLKEAEQLGN  60
   61 HVVGANLNNE QFWLGAQRRT ECLENNDWKP PCTRDKIFEW MNNVATDFRS EWWKKNNNLH 120
  121 SPNPSGTGQR CLSFAFGDLW WSYKGHTGFL DDIECHTELR YFCSKMAPFT ECEENCD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.39794
Match: 1sl6A
Description: Crystal Structure of a fragment of DC-SIGNR (containg the carbohydrate recognition domain and two repeats of the neck) complexed with Lewis-x.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.13629480035749 bayes_pls_golite062009
carbohydrate binding 0.44675717945952 bayes_pls_golite062009
protein binding 0.059857076934361 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle