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View Structure Prediction Details

Protein: hrpf-1
Organism: Caenorhabditis elegans
Length: 549 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hrpf-1.

Description E-value Query
Range
Subject
Range
gi|73981470 - gi|73981470|ref|XP_862492.1| PREDICTED: similar to trinucleotide repeat containing 4 isoform 13 [Can...
202.0 [0..6] [548..8]

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Predicted Domain #1
Region A:
Residues: [1-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTAYEVQCR GLPWEATEQE LRDFFGNNGI ESLEIPRRNG RTSGDAKVVF TNEEDYNNAL  60
   61 KKDREHLGSR YIEVFPAGGA PTRRGDRGER GDRGDRDHYR SRGAPPRDRY SDRGGPRSSG 120
  121 PDSIVRLRGL PFSVTSRDIS DFLAPLPIVR DGILLPDQQR ARPGGEAYVC FETMESVQIA 180
  181 KQRHMKNIGH RYIEVFEATH RDLSRFAEEN DLRVPRF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.69897
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [218-371]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPPPFASAPQ TAPRGAYDPY SQPTDPYRNA TDYRRAAEPE DPYARSRAPS VQDYGVRASY  60
   61 DPYTQPAAPV SSYPSQQQPS AGYYDNYAPK TAYESYGRER GPDPRDVRDP RDSRMPDPRD 120
  121 SRALSDPYAA ESRYSEYGYE SREPYWRGGS GGPP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [372-549]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIGGGVGGGG APLAPTGRDP YSVGESWANG AGGPGGPPPV SSDRDRYGSG GYASEPYAQR  60
   61 EAGGAMRRSE YGRPDDRYSK PEPYGYSRDR DYGAPQNQHF VLRMRGVPFR ASEADVYDFF 120
  121 HPIRPNQVEL LRDHQFQRPS GDARVIFYNR KDYDDALMKD KQYMGERYIE MIPDNGRY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.69897
Match: 2f3jA
Description: No description for 2f3jA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle