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View Structure Prediction Details

Protein: daf-16
Organism: Caenorhabditis elegans
Length: 530 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for daf-16.

Description E-value Query
Range
Subject
Range
gi|7506727 - gi|7506727|pir||T37204 hypothetical protein R13H8.1 - Caenorhabditis elegans
210.0 [0..1] [530..1]

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Predicted Domain #1
Region A:
Residues: [1-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDSIDDDFP PEPRGRCYTW PMQQYIYQES SATIPHHHLN QHNNPYHPMH PHHQLPHMQQ  60
   61 LPQPLLNLNM TTLTSSGSSV ASSIGGGAQC SPCASGSSTA ATNSSQQQQT VGQMLAASVP 120
  121 CSSSGMTLGM SLNLSQGGGP MPAKKKRCRK K

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [152-268]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTDQLAQKKP NPWGEESYSD IIAKALESAP DGRLKLNEIY QWFSDNIPYF GERSSPEEAA  60
   61 GWKNSIRHNL SLHSRFMRIQ NEGAGKSSWW VINPDAKPGR NPRRTRERSN TIETTTK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.0
Match: 1e17A
Description: Afx (Foxo4)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.835523092977445 bayes_pls_golite062009
transcription regulator activity 0.4843036104266 bayes_pls_golite062009
nucleic acid binding 0.37117756729668 bayes_pls_golite062009
DNA binding 0.3118855114645 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [269-530]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQLEKSRRGA KKRIKERALM GSLHSTLNGN SIAGSIQTIS HDLYDDDSMQ GAFDNVPSSF  60
   61 RPRTQSNLSI PGSSSRVSPA IGSDIYDDLE FPSWVGESVP AIPSDIVDRT DQMRIDATTH 120
  121 IGGVQIKQES KPIKTEPIAP PPSYHELNSV RGSCAQNPLL RNPIVPSTNF KPMPLPGAYG 180
  181 NYQNGGITPI NWLSTSNSSP LPGIQSCGIV AAQHTVASSS ALPIDLENLT LPDQPLMDTM 240
  241 DVDALIRHEL SQAGGQHIHF DL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle