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View Structure Prediction Details

Protein: elt-2
Organism: Caenorhabditis elegans
Length: 433 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for elt-2.

Description E-value Query
Range
Subject
Range
RPB1_CAEBR - DNA-directed RNA polymerase II subunit RPB1 OS=Caenorhabditis briggsae GN=rpb-1 PE=3 SV=2
gi|157759005 - gi|157759005|ref|XP_001671846.1| Hypothetical protein CBG05355 [Caenorhabditis briggsae AF16]
158.0 [0..11] [327..1492]

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Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNNYNDNVN GWAEMEPSQP MGGLRLPTQN MDPPEQNNES QLSELPRMKI DNDYASPIER  60
   61 QSVITSGTNN YEPKVETVTS FFHTGIDYSN FGMLDQTT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [99-238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQPFYPLYSG IPVNTLGTFS GYTNSIYDKP SLYDPSIPTI NIPSTYPTVA PTYECVKCSQ  60
   61 SCGAGMKAVN GGMMCVNCST PKTTYSPPVA YSTSLGQPPI LEIPSEQPTA KIAKQSSKKS 120
  121 SSSNRGSNGS ASRRQGLVCS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [239-336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NCNGTNTTLW RRNAEGDPVC NACGLYFKLH HIPRPTSMKK EGALQTRKRK SKSGDSSTPS  60
   61 TSRARERKFE RASSSTEKAQ RSSNRRAGSA KADRELST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.30103
Match: 2gatA
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.44628241003393 bayes_pls_golite062009
DNA binding 1.94519080035201 bayes_pls_golite062009
nucleic acid binding 1.85629109425119 bayes_pls_golite062009
protein binding 1.72653516930292 bayes_pls_golite062009
binding 1.62447538331668 bayes_pls_golite062009
transcription factor activity 1.37728257720121 bayes_pls_golite062009
transcription activator activity 1.10952708883226 bayes_pls_golite062009
sequence-specific DNA binding 0.78199243307321 bayes_pls_golite062009
catalytic activity 0.472235543748473 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.38848912999406 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [337-433]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAVAAATATY VSHADLYPVS SAAVTLPDQT YSNYYQWNTA ATAGLMMVPN DQNYVYAATN  60
   61 YQTGLRPADN IQVHVMPVQD DETKAAARDL EAVDGDS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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