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View Structure Prediction Details

Protein: obr-2
Organism: Caenorhabditis elegans
Length: 436 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for obr-2.

Description E-value Query
Range
Subject
Range
gi|50737139 - gi|50737139|ref|XP_419165.1| PREDICTED: similar to oxysterol-binding protein-like 1A isoform B; oxys...
477.0 [0..2] [417..744]

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Predicted Domain #1
Region A:
Residues: [1-436]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKLFREKKD MGSPKIQNFK RQTVLHKGQR TRLPATYIAP EDVSIWDIIR PNLGKDFSRF  60
   61 TVPVFMNEPL SFLQRLSENV QYNYLLEKAA KCSDDMERIE YVAAFALATV SANHKRLSKP 120
  121 FNPLLLETFE LERNGVRFLA EQVSHHPPIS AVYAESDEFT VEGTVEPTLG FWMTKLLANP 180
  181 HAHLKLTFKK TGETYSWSAP KCAIYNVIMG KMYMNFTSHM KIESSGTYDA VFSFDNKGYY 240
  241 NHKGGDVHVE GHIFEGKNKI KALYGNWTLF LASCDNEDFK HHRKEYLRMF NETVSEKDQG 300
  301 PVVPGSKILW VSNQIPKLFD DQFHFTNFTL SLNEMYPGMS DTVAPTDSRR RKDMKALEDG 360
  361 KNDEAEEFKH KYEEEQRERR TTKTGDVPMW FAKNDEGHWA YKGGYWDRDY SNCLELFESL 420
  421 ENSSTNSSNS SISSVD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.0
Match: 1zhtA
Description: Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sterol binding 3.12877992228795 bayes_pls_golite062009
steroid binding 2.54679035876403 bayes_pls_golite062009
binding 1.67154210149282 bayes_pls_golite062009
lipid binding 1.46539100663772 bayes_pls_golite062009
oxysterol binding 1.1738554488982 bayes_pls_golite062009
phospholipid binding 0.0867097353003303 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle