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View Structure Prediction Details

Protein: mig-10
Organism: Caenorhabditis elegans
Length: 779 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mig-10.

Description E-value Query
Range
Subject
Range
gi|56207000 - gi|56207000|emb|CAI24283.1| ortholog of human Ras association (RalGDS\/AF-6) and pleckstrin homology...
694.0 [0..62] [634..1]

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Predicted Domain #1
Region A:
Residues: [1-297]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSCEEECDL EVDSDEEDQL FGEKCISLLS SLLPLSSSTL LSNAINLELD EVERPPPLLN  60
   61 VLEEQQFPKV CANIEEENEL EADTEEDIAE TADDEESKDP VEKTENFEPS VTMDTYDFPD 120
  121 PYPVQIRARP QVPPKPPIDT VRYSMNNIKE SADWQLDELL EELEALETQL NSSNGGDQLL 180
  181 LGVSGIPASS SRENVKSIST LPPPPPALSY HQTPQQPQLL HHHNNHLGYQ NGIHQITSIN 240
  241 SAASSCSSPD GDSAFGDSSS TESSNNRCRN SAFSSNDSCR DSLNTPSPTQ VSPRNGE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [298-429]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNAEEAKAQK IRQALEKMKE AKVTKIFVKF FVEDGEALQL LIDERWTVAD TLKQLAEKNH  60
   61 IALMEDHCIV EEYPELYIKR VYEDHEKVVE NIQMWVQDSP NKLYFMRRPD KYAFISRPEL 120
  121 YLLTPKTSDH ME

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.69897
Match: 1wgrA
Description: Solution Structure of the RA Domain of Human Grb7 Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.44703207958213 bayes_pls_golite062009
protein binding 1.14993629560865 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [430-565]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPSGDQWTID VKQKFVSEYF HREPVVPPEM EGFLYLKSDG RKSWKKHYFV LRPSGLYYAP  60
   61 KSKKPTTKDL TCLMNLHSNQ VYTGIGWEKK YKSPTPWCIS IKLTALQMKR SQFIKYICAE 120
  121 DEMTFKKWLV ALRIAK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.522879
Match: 2yryA
Description: No description for 2yryA was found.

Predicted Domain #4
Region A:
Residues: [566-650]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGAELLENYE RACQIRRETL GPASSMSAAS SSTAISEVPH SLSHHQRTPS VASSIQLSSH  60
   61 MMNNPTHPLS VNVRNQSPAS FSVNS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.01
Match: 1pk8A
Description: Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [651-779]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CQQSHPSRTS AKLEIQYDEQ PTGTIKRAPL DVLRRVSRAS TSSPTIPQEE SDSDEEFPAP  60
   61 PPVASVMRMP PPVTPPKPCT PLTSKKAPPP PPKRSDTTKL QSASPMAPAK NDLEAALARR 120
  121 REKMATMEC

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.24
Match: 2j63A
Description: No description for 2j63A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle