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View Structure Prediction Details

Protein: DHLE_BACSU
Organism: Bacillus subtilis
Length: 364 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DHLE_BACSU.

Description E-value Query
Range
Subject
Range
gi|47076782 - gi|47076782|dbj|BAD18325.1| leucine dehydrogenase [Geobacillus stearothermophilus]
339.0 [0..1] [364..1]

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Predicted Domain #1
Region A:
Residues: [1-364]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELFKYMEKY DYEQLVFCQD EQSGLKAIIA IHDTTLGPAL GGTRMWTYEN EEAAIEDALR  60
   61 LARGMTYKNA AAGLNLGGGK TVIIGDPRKD KNEEMFRAFG RYIQGLNGRY ITAEDVGTTV 120
  121 EDMDIIHDET DYVTGISPAF GSSGNPSPVT AYGVYRGMKA AAKAAFGTDS LEGKTIAVQG 180
  181 VGNVAYNLCR HLHEEGANLI VTDINKQSVQ RAVEDFGARA VDPDDIYSQD CDIYAPCALG 240
  241 ATINDDTIKQ LKAKVIAGAA NNQLKETRHG DQIHEMGIVY APDYVINAGG VINVADELYG 300
  301 YNAERALKKV EGIYGNIERV LEISQRDGIP AYLAADRLAE ERIERMRRSR SQFLQNGHSV 360
  361 LSRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.0
Match: 1lehA
Description: Leucine dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor 2.86055037477031 bayes_pls_golite062009
catalytic activity 2.43483529599631 bayes_pls_golite062009
oxidoreductase activity 2.40835256378153 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.78381957137814 bayes_pls_golite062009
glutamate dehydrogenase (NADP+) activity 1.72773061949486 bayes_pls_golite062009
malate dehydrogenase activity 1.29890335901924 bayes_pls_golite062009
malic enzyme activity 0.82576094727244 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.73772847519488 bayes_pls_golite062009
ketol-acid reductoisomerase activity 0.0479950038396302 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle