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View Structure Prediction Details

Protein: ETR1_ARATH
Organism: Arabidopsis thaliana
Length: 738 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ETR1_ARATH.

Description E-value Query
Range
Subject
Range
gi|145411509 - gi|145411509|gb|ABP68413.1| putative ethylene receptor [Cucumis melo]
ETR1_CUCMN - Ethylene receptor 1 OS=Cucumis melo var. cantalupensis GN=ETR1 PE=2 SV=1
608.0 [0..1] [736..1]

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Predicted Domain #1
Region A:
Residues: [1-310]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVCNCIEPQ WPADELLMKY QYISDFFIAI AYFSIPLELI YFVKKSAVFP YRWVLVQFGA  60
   61 FIVLCGATHL INLWTFTTHS RTVALVMTTA KVLTAVVSCA TALMLVHIIP DLLSVKTREL 120
  121 FLKNKAAELD REMGLIRTQE ETGRHVRMLT HEIRSTLDRH TILKTTLVEL GRTLALEECA 180
  181 LWMPTRTGLE LQLSYTLRHQ HPVEYTVPIQ LPVINQVFGT SRAVKISPNS PVARLRPVSG 240
  241 KYMLGEVVAV RVPLLHLSNF QINDWPELST KRYALMVLML PSDSARQWHV HELELVEVVA 300
  301 DQVAVALSHA 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.91
Match: 2o9bA
Description: No description for 2o9bA was found.

Predicted functions:

Term Confidence Notes
binding 1.67984576110273 bayes_pls_golite062009
two-component response regulator activity 1.41577088905201 bayes_pls_golite062009
transcription regulator activity 0.931375605669218 bayes_pls_golite062009
protein binding 0.888256242702267 bayes_pls_golite062009
DNA binding 0.533187513797767 bayes_pls_golite062009
two-component sensor activity 0.466388018187262 bayes_pls_golite062009
protein histidine kinase activity 0.452475261443277 bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor 0.409938237891918 bayes_pls_golite062009
nucleic acid binding 0.387046112137798 bayes_pls_golite062009
signal transducer activity 0.341738261779128 bayes_pls_golite062009
molecular transducer activity 0.341738261779128 bayes_pls_golite062009
transcription factor activity 0.15709070306709 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [311-593]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AILEESMRAR DLLMEQNVAL DLARREAETA IRARNDFLAV MNHEMRTPMH AIIALSSLLQ  60
   61 ETELTPEQRL MVETILKSSN LLATLMNDVL DLSRLEDGSL QLELGTFNLH TLFREVLNLI 120
  121 KPIAVVKKLP ITLNLAPDLP EFVVGDEKRL MQIILNIVGN AVKFSKQGSI SVTALVTKSD 180
  181 TRAADFFVVP TGSHFYLRVK VKDSGAGINP QDIPKIFTKF AQTQSLATRS SGGSGLGLAI 240
  241 SKRFVNLMEG NIWIESDGLG KGCTAIFDVK LGISERSNES KQS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.221849
Match: 2c2aA
Description: Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [594-738]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GIPKVPAIPR HSNFTGLKVL VMDENGVSRM VTKGLLVHLG CEVTTVSSNE ECLRVVSHEH  60
   61 KVVFMDVCMP GVENYQIALR IHEKFTKQRH QRPLLVALSG NTDKSTKEKC MSFGLDGVLL 120
  121 KPVSLDNIRD VLSDLLEPRV LYEGM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.045757
Match: 1dcfA
Description: Receiver domain of the ethylene receptor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
two-component response regulator activity 7.02872640261738 bayes_pls_golite062009
signal transducer activity 4.51666042720644 bayes_pls_golite062009
molecular transducer activity 4.51666042720644 bayes_pls_golite062009
transcription regulator activity 3.44888100104099 bayes_pls_golite062009
protein histidine kinase activity 2.35011582062573 bayes_pls_golite062009
two-component sensor activity 2.32303301074957 bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor 2.28838869071567 bayes_pls_golite062009
binding 1.22427537074115 bayes_pls_golite062009
DNA binding 1.11037597107903 bayes_pls_golite062009
nucleic acid binding 0.93151849951839 bayes_pls_golite062009
transcription factor activity 0.62886970109503 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle