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View Structure Prediction Details

Protein: gi|16974371, gi|...
Organism: Arabidopsis thaliana
Length: 379 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|16974371, gi|....

Description E-value Query
Range
Subject
Range
gi|21592587 - gi|21592587|gb|AAM64536.1| putative indole-3-glycerol phosphate synthase [Arabidopsis thaliana]
308.0 [0..13] [378..25]

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Predicted Domain #1
Region A:
Residues: [1-78]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEAALLSLQP FPSSATQRRL SPFNLHNTLT RPSSYAPLRA QKSGITEGSD SALEAKVSEQ  60
   61 EVGMYQNEVV ESQGIRIR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.0
Match: 1wl8A
Description: Crystal structure of PH1346 protein from Pyrococcus horikoshii
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [79-379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRPPTGPPLH YVGPFEFRLQ NEGNTPRNIL EEIVWHKDKE VAQMKERKPL YSLKKALDNV  60
   61 PPAKDFIGAL RSAHQRTGLP GLIAEVKKAS PSRGILREDF NPVEIAQAYE KGGAACLSVL 120
  121 TDDKYFKGSY ENLQAIMEAG VKCPLLLKEF IVEAWQIYYG RSKGADAVLL IASVLPDLDI 180
  181 KYMIKICKIL GMATLVEVHD EREMDRVLAI EGVELIGINN RNLETFEVDL GITKKLLEGE 240
  241 RGELIRQKDI LVVGESGLFT PEDIAFVQEA GVKAVLVGES LIKQSDPGKA ISTLFGRDVS 300
  301 E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.522879
Match: 1piiA
Description: THREE-DIMENSIONAL STRUCTURE OF THE BIFUNCTIONAL ENZYME PHOSPHORIBOSYLANTHRANILATE ISOMERASE: INDOLEGLYCEROLPHOSPHATE SYNTHASE FROM ESCHERICHIA COLI REFINED AT 2.0 ANGSTROMS RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
tryptophan synthase activity 3.15663465352598 bayes_pls_golite062009
indole-3-glycerol-phosphate synthase activity 3.12120866545322 bayes_pls_golite062009
catalytic activity 2.81275055404078 bayes_pls_golite062009
phosphoribosylanthranilate isomerase activity 2.655130814615 bayes_pls_golite062009
carbon-carbon lyase activity 2.44001937916931 bayes_pls_golite062009
carboxy-lyase activity 1.80978905789979 bayes_pls_golite062009
lyase activity 0.9228652996943 bayes_pls_golite062009
imidazoleglycerol-phosphate synthase activity 0.82314869965119 bayes_pls_golite062009
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity 0.302746738903759 bayes_pls_golite062009
isomerase activity 0.14149405165663 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle