YRC Public Data Repository - Protein Structure Prediction

Protein:	BGLX_ECOLI
Organism:	Escherichia coli
Length:	765 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BGLX_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|110642341, gi... - gi\|110642341\|ref\|YP_670071.1\| periplasmic beta-glucosidase precursor [Escherichia coli 536], gi\|1103...	781.0	[0..1]	[765..25]
gi\|74312656, gi\|... - gi\|74312656\|ref\|YP_311075.1\| beta-D-glucoside glucohydrolase, periplasmic [Shigella sonnei Ss046], g...	781.0	[0..1]	[765..1]
gi\|16503407, gi\|... - gi\|25289432\|pir\|\|AD0778 beta-glucosidase (EC 3.2.1.21) - Salmonella enterica subsp. enterica serovar... gi\|29141195, gi\|... - gi\|29141195\|ref\|NP_804537.1\| periplasmic beta-glucosidase precursor [Salmonella enterica subsp. ente... gi\|213428232 - gi\|213428232\|ref\|ZP_03360982.1\| periplasmic beta-glucosidase precursor [Salmonella enterica subsp. e... gi\|16761109 - gi\|16761109\|ref\|NP_456726.1\| periplasmic beta-glucosidase precursor [Salmonella enterica subsp. ente... gi\|213999821 - gi\|213999821\|ref\|ZP_03410556.1\| periplasmic beta-glucosidase precursor [Salmonella enterica subsp. e...	781.0	[0..1]	[765..1]
gi\|117624335, gi... - gi\|117624335\|ref\|YP_853248.1\| beta-D-glucoside glucohydrolase-like protein [Escherichia coli APEC O1... gi\|237704595, gi... - gi\|237704595\|ref\|ZP_04535076.1\| periplasmic beta-glucosidase [Escherichia sp. 3_2_53FAA], gi\|2269009...	780.0	[0..1]	[765..25]
BGLX_SALTY - Periplasmic beta-glucosidase OS=Salmonella typhimurium GN=bglX PE=3 SV=2 BGLX_SALTY - Periplasmic beta-glucosidase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=bglX... lcl\|NC_016856.1_... - [gene=bglX] [protein=periplasmic beta-D-glucoside glucohydrolase] [protein_id=YP_005238209.1] [locat... BGLX_SALTY - Periplasmic beta-glucosidase OS=Salmonella typhimurium GN=bglX PE=3 SV=2	780.0	[0..1]	[765..1]
gi\|26248511, gi\|... - gi\|26248511\|ref\|NP_754551.1\| periplasmic beta-glucosidase precursor [Escherichia coli CFT073], gi\|26...	780.0	[0..1]	[765..1]
gi\|405863, gi\|744170 - gi\|744170\|prf\|\|2014253AD beta-glucosidase, gi\|405863\|gb\|AAA60495.1\| yohA [Escherichia coli]	780.0	[0..1]	[765..25]
gi\|253323984, gi... - gi\|254288909\|ref\|YP_003054657.1\| beta-D-glucoside glucohydrolase, periplasmic [Escherichia coli BL21... gi\|242377774, gi... - gi\|251785501\|ref\|YP_002999805.1\| hypothetical protein B21_02020 [Escherichia coli BL21], gi\|24237777... gi\|169754478, gi... - gi\|170019550\|ref\|YP_001724504.1\| glycoside hydrolase family 3 protein [Escherichia coli ATCC 8739], ... gi\|253974048, gi... - gi\|254162147\|ref\|YP_003045255.1\| beta-D-glucoside glucohydrolase, periplasmic [Escherichia coli B st... gi\|194436057, gi... - gi\|83588114\|ref\|ZP_00926739.1\| COG1472: Beta-glucosidase-related glycosidases [Escherichia coli 101-...	779.0	[0..1]	[765..1]
gi\|91211419, gi\|... - gi\|91211419\|ref\|YP_541405.1\| beta-D-glucoside glucohydrolase [Escherichia coli UTI89], gi\|91072993\|g... gi\|218365820, gi... - gi\|218559051\|ref\|YP_002391964.1\| beta-D-glucoside glucohydrolase, periplasmic [Escherichia coli S88]...	779.0	[0..1]	[765..1]
gi\|191165415, gi... - gi\|191165415\|ref\|ZP_03027257.1\| beta-glucosidase, periplasmic [Escherichia coli B7A], gi\|190904578\|g... gi\|218361466, gi... - gi\|218554698\|ref\|YP_002387611.1\| beta-D-glucoside glucohydrolase, periplasmic [Escherichia coli IAI1... gi\|75234703, gi\|... - gi\|75234703\|ref\|ZP_00719023.1\| COG1472: Beta-glucosidase-related glycosidases [Escherichia coli E110... gi\|194414734, gi... - gi\|75211549\|ref\|ZP_00711628.1\| COG1472: Beta-glucosidase-related glycosidases [Escherichia coli B171... gi\|193062306, gi... - gi\|193062306\|ref\|ZP_03043401.1\| beta-glucosidase, periplasmic [Escherichia coli E22], gi\|192931972\|g... gi\|157154880, gi... - gi\|75186922\|ref\|ZP_00700189.1\| COG1472: Beta-glucosidase-related glycosidases [Escherichia coli E243... gi\|209919591, gi... - gi\|209919591\|ref\|YP_002293675.1\| beta-D-glucoside glucohydrolase [Escherichia coli SE11], gi\|2099128...	779.0	[0..1]	[765..1]

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Predicted Domain #1

Region A:
Residues: [1-648]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKWLCSVGIA VSLALQPALA DDLFGNHPLT PEARDAFVTE LLKKMTVDEK IGQLRLISVG  60
   61 PDNPKEAIRE MIKDGQVGAI FNTVTRQDIR AMQDQVMELS RLKIPLFFAY DVLHGQRTVF 120
  121 PISLGLASSF NLDAVKTVGR VSAYEAADDG LNMTWAPMVD VSRDPRWGRA SEGFGEDTYL 180
  181 TSTMGKTMVE AMQGKSPADR YSVMTSVKHF AAYGAVEGGK EYNTVDMSPQ RLFNDYMPPY 240
  241 KAGLDAGSGA VMVALNSLNG TPATSDSWLL KDVLRDQWGF KGITVSDHGA IKELIKHGTA 300
  301 ADPEDAVRVA LKSGINMSMS DEYYSKYLPG LIKSGKVTMA ELDDAARHVL NVKYDMGLFN 360
  361 DPYSHLGPKE SDPVDTNAES RLHRKEAREV ARESLVLLKN RLETLPLKKS ATIAVVGPLA 420
  421 DSKRDVMGSW SAAGVADQSV TVLTGIKNAV GENGKVLYAK GANVTSDKGI IDFLNQYEEA 480
  481 VKVDPRSPQE MIDEAVQTAK QSDVVVAVVG EAQGMAHEAS SRTDITIPQS QRDLIAALKA 540
  541 TGKPLVLVLM NGRPLALVKE DQQADAILET WFAGTEGGNA IADVLFGDYN PSGKLPMSFP 600
  601 RSVGQIPVYY SHLNTGRPYN ADKPNKYTSR YFDEANGALY PFGYGLSY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	125.0
Match:	1ex1A
Description:	Beta-D-glucan exohydrolase, N-terminal domain; Beta-D-glucan exohydrolase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity, hydrolyzing O-glycosyl compounds	3.03213713925196	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	3.00088487541785	bayes_pls_golite062009
catalytic activity	1.85569074294201	bayes_pls_golite062009
hydrolase activity	1.15751720508639	bayes_pls_golite062009
chitinase activity	0.700083867878222	bayes_pls_golite062009
glucosidase activity	0.528679164808812	bayes_pls_golite062009
hexosaminidase activity	0.220458268933622	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [649-765]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTFTVSDVKL SAPTMKRDGK VTASVQVTNT GKREGATVVQ MYLQDVTASM SRPVKQLKGF  60
   61 EKITLKPGET QTVSFPIDIE ALKFWNQQMK YDAEPGKFNV FIGTDSARVK KGEFELL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: